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HomoloGene:3402. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   FANCG,  H.sapiens
Fanconi anemia, complementation group G
    NP_004620.1
622 aa
   FANCG,  P.troglodytes
Fanconi anemia, complementation group G
    XP_001165190.1
622 aa
   FANCG,  M.mulatta
Fanconi anemia, complementation group G
    XP_001092322.1
622 aa
   FANCG,  C.lupus
Fanconi anemia, complementation group G
    XP_854703.1
806 aa
   FANCG,  B.taurus
Fanconi anemia, complementation group G
    NP_001095757.1
570 aa
   Fancg,  M.musculus
Fanconi anemia, complementation group G
    NP_444311.1
623 aa
   Fancg,  R.norvegicus
Fanconi anemia, complementation group G
    XP_006238187.1
632 aa
   FANCG,  G.gallus
Fanconi anemia, complementation group G
    NP_989709.1
648 aa
   fancg,  X.tropicalis
Fanconi anemia, complementation group G
    NP_001120193.1
631 aa
   fancg,  D.rerio
Fanconi anemia, complementation group G
    NP_991202.1
617 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Fanconi anemia, complementation group G.



Publications
Articles associated with genes and sequences of this homology group.

Evolutionary clues to the molecular function of fanconi anemia genes.
Blom E, et al. Acta Haematol 108, 231-6 (2002).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
NrfG (COG0457)
  FOG: TPR repeat [General function prediction only].
TPR (cd00189)
  Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]-X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, ...
TPR_11 (pfam13414)
  TPR repeat.
TPR_1 (cl02429)
  Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Fancg includes H.sapiens FANCG and R.norvegicus Fancg.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (12 transcripts, 9 species)
Actinopterygii - bony fishes (2 transcripts, 2 species)
Aves - birds (1 transcript, 1 species)

 

 

 

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