Display Settings:

Format

Send to:

Choose Destination
We are sorry, but NCBI web applications do not support your browser and may not function properly. More information
HomoloGene:38295. Gene conserved in Eukaryota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   PARK7,  H.sapiens
parkinson protein 7
    NP_009193.2
189 aa
   PARK7,  C.lupus
parkinson protein 7
    XP_859031.1
189 aa
   PARK7,  B.taurus
parkinson protein 7
    NP_001015572.1
189 aa
   Park7,  M.musculus
Parkinson disease (autosomal recessive, early onset) 7
    NP_065594.2
189 aa
   Park7,  R.norvegicus
parkinson protein 7
    NP_001264180.1
189 aa
   PARK7,  G.gallus
Parkinson disease (autosomal recessive, early onset) 7
    NP_989916.1
189 aa
   park7,  X.tropicalis
parkinson protein 7
    NP_001015851.1
189 aa
   park7,  D.rerio
parkinson disease (autosomal recessive, early onset) 7
    NP_001005938.1
189 aa
   dj-1beta,  D.melanogaster
dj-1beta
    NP_651825.3
205 aa
   DJ-1alpha,  D.melanogaster
DJ-1alpha
    NP_610916.1
217 aa
   djr-1.1,  C.elegans
djr-1.1
    NP_493696.1
187 aa
   djr-1.2,  C.elegans
djr-1.2
    NP_504132.1
186 aa
   SPAC22E12.03c,  S.pombe
SPAC22E12.03c
    NP_594829.1
191 aa
   AT3G14990,  A.thaliana
AT3G14990
    NP_188117.1
392 aa
   AT1G53280,  A.thaliana
AT1G53280
    NP_564626.1
438 aa
   Os01g0217800,  O.sativa
Os01g0217800
    NP_001042407.2
428 aa
   Os06g0531200,  O.sativa
Os06g0531200
    NP_001057783.2
394 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Amyotrophic lateral sclerosis-Parkinsonism/dementia complex 2.
Parkinson disease 7, autosomal recessive early-onset.



Publications
Articles associated with genes and sequences of this homology group.

Evidence of oxidative stress in young and aged DJ-1-deficient mice.
Raman AV, et al. FEBS Lett 587, 1562-70 (2013).
Expression of DJ-1 proteins in placentas from women with severe preeclampsia.
Kwon HS, et al. Eur J Obstet Gynecol Reprod Biol 168, 40-4 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
not_thiJ (TIGR01383)
  DJ-1 family protein.
GAT_1 (cl00020)
  Type 1 glutamine amidotransferase (GATase1)-like domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Park7 includes H.sapiens PARK7 and R.norvegicus Park7.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (19 transcripts, 17 species)
Actinopterygii - bony fishes (10 transcripts, 8 species)
Aves - birds (4 transcripts, 2 species)
Amphibia - amphibians (3 transcripts, 2 species)
Ascidiacea - tunicates (1 transcript, 1 species)
Hyperoartia - vertebrates (1 transcript, 1 species)

Arthropoda
Insecta - insects (12 transcripts, 10 species)
Arachnida - arachnids (2 transcripts, 2 species)
Branchiopoda - crustaceans (1 transcript, 1 species)
Malacostraca - crustaceans (1 transcript, 1 species)
Maxillopoda - crustaceans (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (3 transcripts, 2 species)

Platyhelminthes
Trematoda - flatworms (2 transcripts, 2 species)
Turbellaria - flatworms (1 transcript, 1 species)

Mollusca
Gastropoda - gastropods (2 transcripts, 2 species)

Cnidaria
Hydrozoa - hydrozoans (1 transcript, 1 species)
Anthozoa - anthozoans (1 transcript, 1 species)

Annelida
Polychaeta - segmented worms (2 transcripts, 1 species)

Porifera
Demospongiae - sponges (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (1 transcript, 1 species)

Streptophyta
Liliopsida - monocots (11 transcripts, 7 species)
Eudicotyledons - eudicots (1 transcript, 1 species)
Bryopsida - mosses (1 transcript, 1 species)
Coniferopsida - conifers (1 transcript, 1 species)

Oomycetes
Peronosporales - oomycetes (2 transcripts, 1 species)

Bacillariophyta
Bacillariophyceae - diatoms (1 transcript, 1 species)

Ascomycota
Pezizomycetes - ascomycetes (1 transcript, 1 species)

Apicomplexa
Coccidia - apicomplexans (1 transcript, 1 species)

 

 

 

Write to the Help Desk