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HomoloGene:21148. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   LNPEP,  H.sapiens
leucyl/cystinyl aminopeptidase
    NP_005566.2
1025 aa
   LNPEP,  P.troglodytes
leucyl/cystinyl aminopeptidase
    XP_517842.3
1013 aa
   LNPEP,  M.mulatta
leucyl/cystinyl aminopeptidase
    XP_001092287.2
1025 aa
   LNPEP,  C.lupus
leucyl/cystinyl aminopeptidase
    XP_005618126.1
1037 aa
   LNPEP,  B.taurus
leucyl/cystinyl aminopeptidase
    XP_002689456.2
1026 aa
   Lnpep,  M.musculus
leucyl/cystinyl aminopeptidase
    NP_766415.1
1025 aa
   LNPEP,  G.gallus
leucyl/cystinyl aminopeptidase
    XP_424862.3
1024 aa
   lnpep,  X.tropicalis
leucyl/cystinyl aminopeptidase
    XP_002933474.1
1024 aa
   lnpep,  D.rerio
leucyl/cystinyl aminopeptidase
    NP_955915.1
1003 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Identification of a missense variant in LNPEP that confers psoriasis risk.
Cheng H, et al. J Invest Dermatol 134, 359-65 (2014).
Leucyl/cystinyl aminopeptidase gene variants in septic shock.
Nakada TA, et al. Chest 139, 1042-9 (2011).
Oxytocin hypersensitivity in pregnant P-LAP deficient mice.
Ishii M, et al. Life Sci 84, 668-72 (2009).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
DUF3358 (pfam11838)
  Domain of unknown function (DUF3358).
ERAP1_C (pfam11838)
  ERAP1-like C-terminal domain.
GluZincin (cl14813)
  Peptidase Gluzincin family (thermolysin-like proteinases, TLPs) includes peptidases M1, M2, M3, M4, M13, M32 and M36 (fungalysins).



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Lnpep includes H.sapiens LNPEP and R.norvegicus Lnpep.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (8 transcripts, 8 species)
Actinopterygii - bony fishes (3 transcripts, 3 species)
Aves - birds (2 transcripts, 1 species)
Amphibia - amphibians (1 transcript, 1 species)

Arthropoda
Insecta - insects (1 transcript, 1 species)

 

 

 

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