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HomoloGene:3211. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   CEBPA,  H.sapiens
CCAAT/enhancer binding protein (C/EBP), alpha
    NP_001274353.1
393 aa
   CEBPA,  P.troglodytes
CCAAT/enhancer binding protein (C/EBP), alpha
    XP_001154519.2
255 aa
   LOC717153,  M.mulatta
CCAAT/enhancer-binding protein alpha-like
    XP_001108401.1
316 aa
   CEBPA,  B.taurus
CCAAT/enhancer binding protein (C/EBP), alpha
    NP_789741.2
353 aa
   Cebpa,  M.musculus
CCAAT/enhancer binding protein (C/EBP), alpha
    NP_031704.2
359 aa
   Cebpa,  R.norvegicus
CCAAT/enhancer binding protein (C/EBP), alpha
    NP_036656.1
358 aa
   CEBPA,  G.gallus
CCAAT/enhancer binding protein (C/EBP), alpha
    NP_001026630.1
324 aa
   cebpa,  X.tropicalis
CCAAT/enhancer binding protein (C/EBP), alpha
    NP_001011044.1
297 aa
   cebpa,  D.rerio
CCAAT/enhancer binding protein (C/EBP), alpha
    NP_571960.1
288 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Leukemia, acute myeloid.



Publications
Articles associated with genes and sequences of this homology group.

Initiation of MLL-rearranged AML is dependent on C/EBPα.
Ohlsson E, et al. J Exp Med 211, 5-13 (2014).
C/EBPα regulates osteoclast lineage commitment.
Chen W, et al. Proc Natl Acad Sci U S A 110, 7294-9 (2013).
C/EBPα is required for development of dendritic cell progenitors.
Welner RS, et al. Blood 121, 4073-81 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
B_zip1 (cl02576)
  basic leucine zipper DNA-binding and multimerization region of GCN4 and related proteins.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Cebpa includes H.sapiens CEBPA and R.norvegicus Cebpa.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (7 transcripts, 6 species)
Actinopterygii - bony fishes (6 transcripts, 6 species)
Amphibia - amphibians (2 transcripts, 2 species)
Aves - birds (1 transcript, 1 species)

 

 

 

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