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HomoloGene:64844. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   STARD13,  H.sapiens
StAR-related lipid transfer (START) domain containing 13
    NP_821074.1
1113 aa
   STARD13,  P.troglodytes
StAR-related lipid transfer (START) domain containing 13
    XP_003314160.1
1105 aa
   STARD13,  M.mulatta
StAR-related lipid transfer (START) domain containing 13
    XP_001102223.1
1113 aa
   STARD13,  C.lupus
StAR-related lipid transfer (START) domain containing 13
    XP_849359.2
1122 aa
   STARD13,  B.taurus
StAR-related lipid transfer (START) domain containing 13
    NP_001178999.1
1123 aa
   Stard13,  M.musculus
StAR-related lipid transfer (START) domain containing 13
    NP_666370.3
1113 aa
   Stard13,  R.norvegicus
StAR-related lipid transfer (START) domain containing 13
    NP_001102530.1
1112 aa
   STARD13,  G.gallus
StAR-related lipid transfer (START) domain containing 13
    XP_004938815.1
1411 aa
   stard13,  X.tropicalis
StAR-related lipid transfer (START) domain containing 13
    NP_001039232.1
1045 aa
   stard13b,  D.rerio
StAR-related lipid transfer (START) domain containing 13b
    XP_001340114.1
1123 aa
   stard13a,  D.rerio
StAR-related lipid transfer (START) domain containing 13a
    XP_683100.5
1138 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

The STAR of the DLC family.
El-Sitt S & El-Sibai M. J Recept Signal Transduct Res 33, 10-3 (2013).
DLC2/StarD13 plays a role of a tumor suppressor in astrocytoma.
El-Sitt S, et al. Oncol Rep 28, 511-8 (2012).
START-GAP2/DLC2 is localized in focal adhesions via its N-terminal region.
Kawai K, et al. Biochem Biophys Res Commun 380, 736-41 (2009).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
SRPBCC (cl14643)
  START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily.
SAM_superfamily (cl15755)
  SAM (Sterile alpha motif ).
FSIP1 (pfam15554)
  FSIP1 family.
RhoGAP (cl02570)
  RhoGAP: GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when ...
SRPBCC (cl14643)
  START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily.
SAM_superfamily (cl15755)
  SAM (Sterile alpha motif ).



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Stard13 includes H.sapiens STARD13 and R.norvegicus Stard13.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (11 transcripts, 9 species)
Actinopterygii - bony fishes (11 transcripts, 6 species)
Amphibia - amphibians (3 transcripts, 2 species)
Amniota - vertebrates (2 transcripts, 1 species)
Ascidiacea - tunicates (1 transcript, 1 species)
Aves - birds (1 transcript, 1 species)

Arthropoda
Insecta - insects (6 transcripts, 4 species)
Arachnida - arachnids (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (2 transcripts, 1 species)

Cnidaria
Anthozoa - anthozoans (1 transcript, 1 species)

Porifera
Demospongiae - sponges (1 transcript, 1 species)

Annelida
Hirudinida - segmented worms (1 transcript, 1 species)

 

 

 

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