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HomoloGene:1688. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   KCNJ6,  H.sapiens
potassium inwardly-rectifying channel, subfamily J, member 6
    NP_002231.1
423 aa
   KCNJ6,  P.troglodytes
potassium inwardly-rectifying channel, subfamily J, member 6
    XP_001170389.1
423 aa
   KCNJ6,  M.mulatta
potassium inwardly-rectifying channel, subfamily J, member 6
    XP_001083031.1
423 aa
   KCNJ6,  C.lupus
potassium inwardly-rectifying channel, subfamily J, member 6
    XP_544881.3
423 aa
   KCNJ6,  B.taurus
potassium inwardly-rectifying channel, subfamily J, member 6
    XP_002685215.2
407 aa
   Kcnj6,  M.musculus
potassium inwardly-rectifying channel, subfamily J, member 6
    NP_034736.2
425 aa
   Kcnj6,  R.norvegicus
potassium inwardly-rectifying channel, subfamily J, member 6
    NP_037324.1
425 aa
   KCNJ6,  G.gallus
potassium inwardly-rectifying channel, subfamily J, member 6
    XP_004934603.1
423 aa
   kcnj9,  X.tropicalis
potassium inwardly-rectifying channel, subfamily J, member 9
    NP_001096554.1
407 aa
   kcnj6,  D.rerio
potassium inwardly-rectifying channel, subfamily J, member 6
    XP_697984.5
412 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Molecular mechanism underlying ethanol activation of G-protein-gated inwardly rectifying potassium channels.
Bodhinathan K & Slesinger PA. Proc Natl Acad Sci U S A 110, 18309-14 (2013).
X-ray structure of the mammalian GIRK2-βγ G-protein complex.
Whorton MR & MacKinnon R. Nature 498, 190-7 (2013).
Generation and survival of midbrain dopaminergic neurons in weaver mice.
Martí J, et al. Int J Dev Neurosci 25, 299-307 (2007).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Ion_trans (pfam00520)
  Ion transport protein.
IRK (pfam01007)
  Inward rectifier potassium channel.
IRK (pfam01007)
  Inward rectifier potassium channel.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Kcnj6 includes H.sapiens KCNJ6 and R.norvegicus Kcnj6.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (9 transcripts, 8 species)
Actinopterygii - bony fishes (3 transcripts, 2 species)
Ascidiacea - tunicates (2 transcripts, 2 species)
Aves - birds (1 transcript, 1 species)

Arthropoda
Insecta - insects (1 transcript, 1 species)
Arachnida - arachnids (1 transcript, 1 species)

Mollusca
Gastropoda - gastropods (2 transcripts, 1 species)

Annelida
Hirudinida - segmented worms (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (1 transcript, 1 species)

 

 

 

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