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HomoloGene:55526. Gene conserved in Boreoeutheria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   IFNG,  H.sapiens
interferon, gamma
    NP_000610.2
166 aa
   IFNG,  P.troglodytes
interferon, gamma
    NP_001180594.1
166 aa
   IFNG,  M.mulatta
interferon, gamma
    NP_001028077.1
165 aa
   IFNG,  C.lupus
interferon gamma
    NP_001003174.1
166 aa
   IFNG,  B.taurus
interferon, gamma
    NP_776511.1
166 aa
   Ifng,  M.musculus
interferon gamma
    NP_032363.1
155 aa
   Ifng,  R.norvegicus
interferon gamma
    NP_620235.1
156 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Interferon, immune, deficiency.
TSC2 angiomyolipomas, renal, modifier of.
Tuberculosis, susceptibility to.
Aplastic anemia.
AIDS, rapid progression to.



Publications
Articles associated with genes and sequences of this homology group.

Interferon-γ and systemic autoimmunity.
Pollard KM, et al. Discov Med 16, 123-31 (2013).
Prominent role of IFN-γ in patients with aspirin-exacerbated respiratory disease.
Steinke JW, et al. J Allergy Clin Immunol 132, 856-65.e1-3 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
IFN-gamma (pfam00714)
  Interferon gamma.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Ifng includes H.sapiens IFNG and R.norvegicus Ifng.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (10 transcripts, 10 species)

 

 

 

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