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HomoloGene:7258. Gene conserved in Bilateria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   CCKBR,  H.sapiens
cholecystokinin B receptor
    NP_795344.1
447 aa
   CCKBR,  P.troglodytes
cholecystokinin B receptor
    XP_521813.2
447 aa
   LOC712939,  M.mulatta
gastrin/cholecystokinin type B receptor-like
    XP_001102094.1
416 aa
   CCKBR,  B.taurus
cholecystokinin B receptor
    NP_776687.2
454 aa
   Cckbr,  M.musculus
cholecystokinin B receptor
    NP_031653.1
453 aa
   Cckbr,  R.norvegicus
cholecystokinin B receptor
    NP_037297.1
452 aa
   CCKBR,  G.gallus
cholecystokinin B receptor
    NP_001001742.1
436 aa
   si:dkey-1h24.2,  D.rerio
si:dkey-1h24.2
    NP_001108186.2
444 aa
   LOC100331465,  D.rerio
cholecystokinin receptor-like
    XP_002663361.2
442 aa
   CCKLR-17D1,  D.melanogaster
CCK-like receptor at 17D1
    NP_001097021.1
673 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Downregulation of the CCK-B receptor in pancreatic cancer cells blocks proliferation and promotes apoptosis.
Fino KK, et al. Am J Physiol Gastrointest Liver Physiol 302, G1244-52 (2012).
Rimonabant attenuates amphetamine sensitisation in a CCK2 receptor-dependent manner.
R√ľnkorg K, et al. Behav Brain Res 226, 335-9 (2012).
Menin and JunD regulate gastrin gene expression through proximal DNA elements.
Mensah-Osman EJ, et al. Am J Physiol Gastrointest Liver Physiol 301, G783-90 (2011).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
7tm_1 (pfam00001)
  7 transmembrane receptor (rhodopsin family).
7tm_1 (pfam00001)
  7 transmembrane receptor (rhodopsin family).



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Cckbr includes H.sapiens CCKBR and R.norvegicus Cckbr.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (13 transcripts, 10 species)
Actinopterygii - bony fishes (2 transcripts, 2 species)
Aves - birds (1 transcript, 1 species)

Arthropoda
Insecta - insects (1 transcript, 1 species)

 

 

 

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