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HomoloGene:84442. Gene conserved in Bilateria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   NEK8,  H.sapiens
NIMA-related kinase 8
    NP_835464.1
692 aa
   NEK8,  P.troglodytes
NIMA (never in mitosis gene a)- related kinase 8
    XP_511801.3
646 aa
   NEK8,  M.mulatta
NIMA (never in mitosis gene a)- related kinase 8
    XP_001106986.2
692 aa
   NEK8,  C.lupus
NIMA-related kinase 8
    XP_548291.3
699 aa
   NEK8,  B.taurus
NIMA (never in mitosis gene a)- related kinase 8
    NP_001179652.1
698 aa
   Nek8,  M.musculus
NIMA (never in mitosis gene a)-related expressed kinase 8
    NP_543125.1
698 aa
   Nek8,  R.norvegicus
NIMA-related kinase 8
    NP_001099274.1
698 aa
   NEK8,  G.gallus
NIMA (never in mitosis gene a)- related kinase 8
    XP_415822.3
698 aa
   nek8,  X.tropicalis
NIMA-related kinase 8
    NP_001006906.1
697 aa
   nek8,  D.rerio
NIMA (never in mitosis gene a)-related kinase 8
    NP_620776.1
697 aa
   niki,  D.melanogaster
nimA-like kinase
    NP_651293.1
841 aa
   AgaP_AGAP006872,  A.gambiae
AgaP_AGAP006872
    XP_308885.4
792 aa
   nekl-1,  C.elegans
nekl-1
    NP_490968.2
998 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Nephronophthisis 9.



Publications
Articles associated with genes and sequences of this homology group.




Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
RCC1 (pfam00415)
  Regulator of chromosome condensation (RCC1) repeat.
RCC1_2 (pfam13540)
  Regulator of chromosome condensation (RCC1) repeat.
RCC1 (pfam00415)
  Regulator of chromosome condensation (RCC1) repeat.
RCC1_2 (pfam13540)
  Regulator of chromosome condensation (RCC1) repeat.
PKc_like (cl09925)
  Protein Kinases, catalytic domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Nek8 includes H.sapiens NEK8 and R.norvegicus Nek8.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (8 transcripts, 7 species)
Ascidiacea - tunicates (3 transcripts, 3 species)
Actinopterygii - bony fishes (3 transcripts, 3 species)
Aves - birds (2 transcripts, 1 species)
Amphibia - amphibians (2 transcripts, 2 species)

Arthropoda
Insecta - insects (1 transcript, 1 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

Cnidaria
Hydrozoa - hydrozoans (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (1 transcript, 1 species)

Annelida
Polychaeta - segmented worms (1 transcript, 1 species)

 

 

 

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