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HomoloGene:69460. Gene conserved in Bilateria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   CANT1,  H.sapiens
calcium activated nucleotidase 1
    NP_001153244.1
401 aa
   CANT1,  P.troglodytes
calcium activated nucleotidase 1
    XP_001158629.1
401 aa
   CANT1,  M.mulatta
calcium activated nucleotidase 1
    XP_001109215.1
401 aa
   CANT1,  B.taurus
calcium activated nucleotidase 1
    XP_002696200.2
501 aa
   Cant1,  M.musculus
calcium activated nucleotidase 1
    NP_001020788.1
403 aa
   Cant1,  R.norvegicus
calcium activated nucleotidase 1
    NP_653355.1
403 aa
   cant1,  X.tropicalis
calcium activated nucleotidase 1
    NP_988940.1
400 aa
   cant1a,  D.rerio
calcium activated nucleotidase 1a
    NP_999908.1
404 aa
   CG5276,  D.melanogaster
CG5276
    NP_650074.1
419 aa
   AgaP_AGAP001217,  A.gambiae
AgaP_AGAP001217
    XP_321938.3
429 aa
   apy-1,  C.elegans
apy-1
    NP_509283.1
355 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Desbuquois dysplasia.



Publications
Articles associated with genes and sequences of this homology group.

Identification of CANT1 mutations in Desbuquois dysplasia.
Huber C, et al. Am J Hum Genet 85, 706-10 (2009).
Clinical and genetic heterogeneity in Desbuquois dysplasia.
Faivre L, et al. Am J Med Genet A 128A, 29-32 (2004).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Apyrase (cl05556)
  This family consists of several eukaryotic apyrase proteins (EC:3.6.1.5). The salivary apyrases of blood-feeding arthropods are nucleotide hydrolysing enzymes implicated in the inhibition of host platelet aggregation through the hydrolysis of extracellular adenosine diphosphate..



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Cant1 includes H.sapiens CANT1 and R.norvegicus Cant1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Actinopterygii - bony fishes (13 transcripts, 8 species)
Mammalia - mammals (7 transcripts, 7 species)
Ascidiacea - tunicates (3 transcripts, 2 species)
Aves - birds (2 transcripts, 2 species)
Amphibia - amphibians (2 transcripts, 2 species)
Cephalochordata - lancelets (1 transcript, 1 species)

Arthropoda
Insecta - insects (15 transcripts, 11 species)
Branchiopoda - crustaceans (2 transcripts, 1 species)
Maxillopoda - crustaceans (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (7 transcripts, 2 species)

Cnidaria
Anthozoa - anthozoans (2 transcripts, 1 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

Porifera
Demospongiae - sponges (1 transcript, 1 species)

Annelida
Hirudinida - segmented worms (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (1 transcript, 1 species)

Oomycetes
Peronosporales - oomycetes (1 transcript, 1 species)
Pythiales - oomycetes (1 transcript, 1 species)

Bacillariophyta
Bacillariophyceae - diatoms (1 transcript, 1 species)

Streptophyta
Liliopsida - monocots (1 transcript, 1 species)

Apicomplexa
Coccidia - apicomplexans (1 transcript, 1 species)

 

 

 

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