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HomoloGene:1382. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   CLU,  H.sapiens
clusterin
    NP_001822.3
449 aa
   CLU,  P.troglodytes
clusterin
    XP_519677.2
501 aa
   CLU,  M.mulatta
clusterin
    XP_001109522.2
501 aa
   CLU,  C.lupus
clusterin
    NP_001003370.1
445 aa
   CLU,  B.taurus
clusterin
    NP_776327.1
439 aa
   Clu,  M.musculus
clusterin
    NP_038520.2
448 aa
   Clu,  R.norvegicus
clusterin
    NP_444180.2
447 aa
   CLU,  G.gallus
clusterin
    NP_990231.1
448 aa
   clu,  X.tropicalis
clusterin
    NP_001004936.1
445 aa
   clu,  D.rerio
clusterin
    NP_957096.1
448 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Clusterin decreases hepatic SREBP-1c expression and lipid accumulation.
Seo HY, et al. Endocrinology 154, 1722-30 (2013).
Essential role of clusterin in pancreas regeneration.
Lee S, et al. Dev Dyn 240, 605-15 (2011).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
CLb (smart00030)
  CLUSTERIN Beta chain.
CLa (smart00035)
  CLUSTERIN alpha chain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Clu includes H.sapiens CLU and R.norvegicus Clu.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (20 transcripts, 16 species)
Actinopterygii - bony fishes (6 transcripts, 6 species)
Aves - birds (3 transcripts, 2 species)

Arthropoda
Arachnida - arachnids (1 transcript, 1 species)

Apicomplexa
Coccidia - apicomplexans (1 transcript, 1 species)

 

 

 

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