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HomoloGene:30967. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   ATXN7,  H.sapiens
ataxin 7
    NP_001170858.1
945 aa
   ATXN7,  P.troglodytes
ataxin 7
    XP_001174619.2
939 aa
   ATXN7,  C.lupus
ataxin 7
    XP_005632413.1
923 aa
   ATXN7,  B.taurus
ataxin 7
    XP_002697032.2
832 aa
   Atxn7,  M.musculus
ataxin 7
    NP_631973.3
867 aa
   Atxn7,  R.norvegicus
ataxin 7
    XP_006251790.1
920 aa
   ATXN7,  G.gallus
ataxin 7
    XP_004944715.1
862 aa
   atxn7,  X.tropicalis
ataxin 7
    NP_001106501.1
849 aa
   LOC100001490,  D.rerio
ataxin-7-like
    XP_001341475.5
812 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Spinocerebellar ataxia-7.



Publications
Articles associated with genes and sequences of this homology group.

Ataxin-7 associates with microtubules and stabilizes the cytoskeletal network.
Nakamura Y, et al. Hum Mol Genet 21, 1099-110 (2012).
Spinocerebellar ataxia type 7.
Martin JJ. Handb Clin Neurol 103, 475-91 (2012).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
SCA7 (pfam08313)
  SCA7, zinc-binding domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Atxn7 includes H.sapiens ATXN7 and R.norvegicus Atxn7.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (14 transcripts, 8 species)
Actinopterygii - bony fishes (1 transcript, 1 species)
Aves - birds (1 transcript, 1 species)
Amphibia - amphibians (1 transcript, 1 species)

 

 

 

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