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HomoloGene:695. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   NQO1,  H.sapiens
NAD(P)H dehydrogenase, quinone 1
    NP_000894.1
274 aa
   NQO1,  P.troglodytes
NAD(P)H dehydrogenase, quinone 1
    XP_523404.3
240 aa
   NQO1,  M.mulatta
NAD(P)H dehydrogenase, quinone 1
    XP_002802551.1
274 aa
   NQO1,  C.lupus
NAD(P)H dehydrogenase, quinone 1
    XP_853617.3
273 aa
   NQO1,  B.taurus
NAD(P)H dehydrogenase, quinone 1
    NP_001029707.1
274 aa
   Nqo1,  M.musculus
NAD(P)H dehydrogenase, quinone 1
    NP_032732.3
274 aa
   Nqo1,  R.norvegicus
NAD(P)H dehydrogenase, quinone 1
    NP_058696.2
274 aa
   NQO1,  G.gallus
NAD(P)H dehydrogenase, quinone 1
    NP_001264548.1
274 aa
   nqo1,  X.tropicalis
NAD(P)H dehydrogenase, quinone 1
    NP_001016468.1
280 aa
   nqo1,  D.rerio
NAD(P)H dehydrogenase, quinone 1
    NP_001191201.1
289 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Benzene toxicity, susceptibility to.
Leukemia, post-chemotherapy, susceptibility to.



Publications
Articles associated with genes and sequences of this homology group.

NQO1 prevents radiation-induced aneuploidy by interacting with Aurora-A.
Park MT, et al. Carcinogenesis 34, 2470-85 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Flavodoxin_2 (pfam02525)
  Flavodoxin-like fold.
FMN_red (cl00438)
  NADPH-dependent FMN reductase.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Nqo1 includes H.sapiens NQO1 and R.norvegicus Nqo1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (15 transcripts, 14 species)
Actinopterygii - bony fishes (11 transcripts, 9 species)
Amphibia - amphibians (2 transcripts, 2 species)
Aves - birds (1 transcript, 1 species)

 

 

 

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