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HomoloGene:55681. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   PRKCZ,  H.sapiens
protein kinase C, zeta
    NP_002735.3
592 aa
   PRKCZ,  P.troglodytes
protein kinase C, zeta
    XP_001148501.2
527 aa
   PRKCZ,  C.lupus
protein kinase C, zeta
    XP_849092.1
591 aa
   PRKCZ,  B.taurus
protein kinase C, zeta
    NP_001071301.1
594 aa
   Prkcz,  M.musculus
protein kinase C, zeta
    NP_032886.2
592 aa
   Prkcz,  R.norvegicus
protein kinase C, zeta
    NP_071952.1
592 aa
   PRKCZ,  G.gallus
protein kinase C, zeta
    XP_417561.3
592 aa
   prkcz,  X.tropicalis
protein kinase C, zeta
    NP_001093735.1
583 aa
   prkcz,  D.rerio
protein kinase C, zeta
    NP_001025262.1
599 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Prkcz null mice show normal learning and memory.
Lee AM, et al. Nature 493, 416-9 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
C1 (cl00040)
  Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
PB1 (cl02720)
  The PB1 domain is a modular domain mediating specific protein-protein interactions which play a role in many critical cell processes, such as osteoclastogenesis, angiogenesis, early cardiovascular development, and cell polarity. A canonical PB1-PB1 ...
PKc_like (cl09925)
  Protein Kinases, catalytic domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Prkcz includes H.sapiens PRKCZ and R.norvegicus Prkcz.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (16 transcripts, 15 species)
Actinopterygii - bony fishes (11 transcripts, 5 species)
Aves - birds (3 transcripts, 2 species)
Amphibia - amphibians (3 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)
Ascidiacea - tunicates (1 transcript, 1 species)

Platyhelminthes
Turbellaria - flatworms (4 transcripts, 1 species)
Trematoda - flatworms (3 transcripts, 2 species)

Porifera
Demospongiae - sponges (3 transcripts, 1 species)

Cnidaria
Hydrozoa - hydrozoans (1 transcript, 1 species)
Anthozoa - anthozoans (1 transcript, 1 species)

Arthropoda
Insecta - insects (1 transcript, 1 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

Annelida
Hirudinida - segmented worms (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (1 transcript, 1 species)

Codonosigidae
Monosiga - choanoflagellates (2 transcripts, 1 species)

 

 

 

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