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HomoloGene:55948. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   IKZF1,  H.sapiens
IKAROS family zinc finger 1 (Ikaros)
    NP_006051.1
519 aa
   IKZF1,  P.troglodytes
IKAROS family zinc finger 1 (Ikaros)
    XP_001148911.3
452 aa
   IKZF1,  M.mulatta
DNA-binding protein Ikaros-like
    XP_001082388.2
554 aa
   IKZF1,  C.lupus
IKAROS family zinc finger 1 (Ikaros)
    XP_003432337.1
519 aa
   IKZF1,  B.taurus
IKAROS family zinc finger 1 (Ikaros)
    NP_001098727.1
515 aa
   Ikzf1,  M.musculus
IKAROS family zinc finger 1
    NP_001020768.1
515 aa
   IKZF1,  G.gallus
IKAROS family zinc finger 1 (Ikaros)
    NP_990419.1
518 aa
   ikzf1,  X.tropicalis
IKAROS family zinc finger 1 (Ikaros)
    NP_001015698.1
483 aa
   ikzf1,  D.rerio
IKAROS family zinc finger 1 (Ikaros)
    NP_571061.1
537 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Leukemia, acute lymphoblastic.



Publications
Articles associated with genes and sequences of this homology group.

Ectopic Ikaros expression positively correlates with lung cancer progression.
Zhang Z, et al. Anat Rec (Hoboken) 296, 907-13 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
zf-H2C2_2 (pfam13465)
  Zinc-finger double domain.
zf-C2H2 (cl15478)
  Zinc finger, C2H2 type.
zf-H2C2_2 (cl19539)
  Zinc-finger double domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Ikzf1 includes H.sapiens IKZF1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (9 transcripts, 7 species)
Actinopterygii - bony fishes (8 transcripts, 6 species)
Aves - birds (2 transcripts, 1 species)
Amphibia - amphibians (1 transcript, 1 species)

 

 

 

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