Display Settings:

Format

Send to:

Choose Destination
We are sorry, but NCBI web applications do not support your browser and may not function properly. More information
HomoloGene:55471. Gene conserved in Eukaryota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   SLC11A2,  H.sapiens
solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
    NP_001167596.1
590 aa
   SLC11A2,  P.troglodytes
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
    XP_003313747.1
590 aa
   SLC11A2,  M.mulatta
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
    XP_001082702.1
568 aa
   SLC11A2,  C.lupus
solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
    XP_005636884.1
598 aa
   SLC11A2,  B.taurus
solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
    NP_001094573.1
562 aa
   Slc11a2,  M.musculus
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
    NP_001139633.1
561 aa
   Slc11a2,  R.norvegicus
solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
    NP_037305.2
592 aa
   slc11a2,  X.tropicalis
solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
    NP_001116938.1
553 aa
   slc11a2,  D.rerio
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
    NP_001035460.1
547 aa
   Mvl,  D.melanogaster
Malvolio
    NP_996251.2
605 aa
   AgaP_AGAP012464,  A.gambiae
AgaP_AGAP012464
    XP_315254.3
426 aa
   smf-1,  C.elegans
smf-1
    NP_001024792.2
562 aa
   smf-2,  C.elegans
smf-2
    NP_509131.2
546 aa
   smf-3,  C.elegans
smf-3
    NP_500235.4
560 aa
   NRAMP5,  A.thaliana
NRAMP5
    NP_193614.1
530 aa
   Os12g0581600,  O.sativa
Os12g0581600
    NP_001067135.1
541 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Anemia, hypochromic microcytic.



Publications
Articles associated with genes and sequences of this homology group.

Divalent metal transporter 1 expression and regulation in human placenta.
Li YQ, et al. Biol Trace Elem Res 146, 6-12 (2012).
Tanshinone IIA prevented brain iron dyshomeostasis in cerebral ischemic rats.
Yang L, et al. Cell Physiol Biochem 27, 23-30 (2011).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
MntH (cl15845)
  Mn2+ and Fe2+ transporters of the NRAMP family [Inorganic ion transport and metabolism].



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Slc11a2 includes H.sapiens SLC11A2 and R.norvegicus Slc11a2.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Streptophyta
Eudicotyledons - eudicots (79 transcripts, 28 species)
Liliopsida - monocots (15 transcripts, 9 species)
Coniferopsida - conifers (6 transcripts, 3 species)
Bryopsida - mosses (2 transcripts, 1 species)

Chordata
Mammalia - mammals (17 transcripts, 14 species)
Actinopterygii - bony fishes (16 transcripts, 7 species)
Ascidiacea - tunicates (2 transcripts, 1 species)
Amphibia - amphibians (2 transcripts, 2 species)
Aves - birds (1 transcript, 1 species)
Cephalochordata - lancelets (1 transcript, 1 species)

Arthropoda
Insecta - insects (14 transcripts, 9 species)
Arachnida - arachnids (2 transcripts, 2 species)
Maxillopoda - crustaceans (1 transcript, 1 species)

Platyhelminthes
Trematoda - flatworms (2 transcripts, 2 species)
Turbellaria - flatworms (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (2 transcripts, 1 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

Cnidaria
Anthozoa - anthozoans (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (1 transcript, 1 species)

Ciliophora
Oligohymenophorea - ciliates (1 transcript, 1 species)

 

 

 

Write to the Help Desk