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HomoloGene:55473. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   NOS2,  H.sapiens
nitric oxide synthase 2, inducible
    NP_000616.3
1153 aa
   NOS2,  P.troglodytes
nitric oxide synthase 2, inducible
    XP_001148238.1
1153 aa
   NOS2,  M.mulatta
nitric oxide synthase 2, inducible
    XP_001106245.1
1153 aa
   NOS2,  C.lupus
nitric oxide synthase 2, inducible
    XP_005624903.1
1157 aa
   NOS2,  B.taurus
nitric oxide synthase 2, inducible
    NP_001070267.1
1156 aa
   Nos2,  M.musculus
nitric oxide synthase 2, inducible
    NP_035057.1
1144 aa
   Nos2,  R.norvegicus
nitric oxide synthase 2, inducible
    NP_036743.3
1147 aa
   LOC497963,  R.norvegicus
similar to Nitric oxide synthase, inducible (NOS type II) (Inducible NO synthase) (Inducible NOS) (iNOS)
    XP_006247011.1
1146 aa
   NOS2,  G.gallus
nitric oxide synthase 2, inducible
    NP_990292.1
1136 aa
   nos2,  X.tropicalis
nitric oxide synthase 2, inducible
    XP_002935342.2
1160 aa
   nos2a,  D.rerio
nitric oxide synthase 2a, inducible
    NP_001098407.1
1079 aa
   nos2b,  D.rerio
nitric oxide synthase 2b, inducible
    NP_001106973.1
1077 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Hypertension, susceptibility to.
Malaria, resistance to.
Malaria, resistance to.



Publications
Articles associated with genes and sequences of this homology group.

Genetic and clinical contributions to cerebral palsy: a multi-variable analysis.
O'Callaghan ME, et al. J Paediatr Child Health 49, 575-81 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
FNR_like (cl06868)
  Ferredoxin reductase (FNR), an FAD and NAD(P) binding protein, was intially identified as a chloroplast reductase activity, catalyzing the electron transfer from reduced iron-sulfur protein ferredoxin to NADP+ as the final step in the electron transport ...
NOS_oxygenase (cl00254)
  Nitric oxide synthase (NOS) produces nitric oxide (NO) by catalyzing a five-electron heme-based oxidation of a guanidine nitrogen of L-arginine to L-citrulline via two successive monooxygenation reactions producing N(omega)-hydroxy-L-arginine (NHA) as an ...
FMN_red (cl00438)
  NADPH-dependent FMN reductase.
FNR_like (cl06868)
  Ferredoxin reductase (FNR), an FAD and NAD(P) binding protein, was intially identified as a chloroplast reductase activity, catalyzing the electron transfer from reduced iron-sulfur protein ferredoxin to NADP+ as the final step in the electron transport ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Nos2 includes H.sapiens NOS2 and R.norvegicus Nos2.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (14 transcripts, 12 species)
Actinopterygii - bony fishes (3 transcripts, 2 species)
Aves - birds (2 transcripts, 2 species)
Amphibia - amphibians (1 transcript, 1 species)

 

 

 

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