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HomoloGene:4785. Gene conserved in Boreoeutheria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   KLF1,  H.sapiens
Kruppel-like factor 1 (erythroid)
    NP_006554.1
362 aa
   KLF1,  P.troglodytes
Kruppel-like factor 1 (erythroid)
    XP_524128.1
362 aa
   KLF1,  M.mulatta
Kruppel-like factor 1 (erythroid)
    XP_001109612.1
362 aa
   KLF1,  C.lupus
Kruppel-like factor 1 (erythroid)
    XP_542040.3
369 aa
   KLF1,  B.taurus
Kruppel-like factor 1 (erythroid)
    NP_001073828.1
372 aa
   Klf1,  M.musculus
Kruppel-like factor 1 (erythroid)
    NP_034765.2
376 aa
   Klf1,  R.norvegicus
Kruppel-like factor 1 (erythroid)
    NP_001100634.1
376 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Blood group--Lutheran inhibitor.



Publications
Articles associated with genes and sequences of this homology group.

Delayed fetal hemoglobin switching in subjects with KLF1 gene mutation.
Satta S, et al. Blood Cells Mol Dis 48, 22-4 (2012).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
zf-H2C2_2 (pfam13465)
  Zinc-finger double domain.
zf-C2H2 (cl15478)
  Zinc finger, C2H2 type.
zf-C2H2 (pfam00096)
  Zinc finger, C2H2 type.
zf-H2C2_2 (cl19539)
  Zinc-finger double domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Klf1 includes H.sapiens KLF1 and R.norvegicus Klf1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (6 transcripts, 6 species)
Amphibia - amphibians (1 transcript, 1 species)

 

 

 

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