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HomoloGene:2496. Gene conserved in Tetrapoda Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   TNFRSF4,  H.sapiens
tumor necrosis factor receptor superfamily, member 4
    NP_003318.1
277 aa
   TNFRSF4,  P.troglodytes
tumor necrosis factor receptor superfamily, member 4
    XP_513705.3
310 aa
   TNFRSF4,  M.mulatta
tumor necrosis factor receptor superfamily, member 4
    XP_001090870.1
277 aa
   TNFRSF4,  C.lupus
tumor necrosis factor receptor superfamily, member 4
    XP_546720.3
273 aa
   TNFRSF4,  B.taurus
tumor necrosis factor receptor superfamily, member 4
    NP_001092513.1
278 aa
   Tnfrsf4,  M.musculus
tumor necrosis factor receptor superfamily, member 4
    NP_035789.1
272 aa
   Tnfrsf4,  R.norvegicus
tumor necrosis factor receptor superfamily, member 4
    NP_037181.1
271 aa
   TNFRSF4,  G.gallus
tumor necrosis factor receptor superfamily, member 4
    XP_004947480.1
287 aa
   tnfrsf4,  X.tropicalis
tumor necrosis factor receptor superfamily, member 4
    XP_004916593.1
280 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

CD134 is a cellular receptor specific for human herpesvirus-6B entry.
Tang H, et al. Proc Natl Acad Sci U S A 110, 9096-9 (2013).
OX40 facilitates control of a persistent virus infection.
Boettler T, et al. PLoS Pathog 8, e1002913 (2012).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
TNFR (cd00185)
  Tumor necrosis factor receptor (TNFR) domain; superfamily of TNF-like receptor domains. When bound to TNF-like cytokines, TNFRs trigger multiple signal transduction pathways, they are involved in inflammation response, apoptosis, autoimmunity and ...
TNFR (cl12111)
  Tumor necrosis factor receptor (TNFR) domain; superfamily of TNF-like receptor domains. When bound to TNF-like cytokines, TNFRs trigger multiple signal transduction pathways, they are involved in inflammation response, apoptosis, autoimmunity and ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Tnfrsf4 includes H.sapiens TNFRSF4 and R.norvegicus Tnfrsf4.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (7 transcripts, 7 species)

 

 

 

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