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HomoloGene:11409. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   ARHGEF11,  H.sapiens
Rho guanine nucleotide exchange factor (GEF) 11
    NP_937879.1
1562 aa
   ARHGEF11,  P.troglodytes
Rho guanine nucleotide exchange factor (GEF) 11
    XP_513900.2
1562 aa
   ARHGEF11,  M.mulatta
Rho guanine nucleotide exchange factor (GEF) 11
    XP_001116843.1
1562 aa
   ARHGEF11,  C.lupus
Rho guanine nucleotide exchange factor (GEF) 11
    XP_005622734.1
1558 aa
   LOC511220,  B.taurus
rho guanine nucleotide exchange factor 11-like
    XP_002686053.3
1263 aa
   Arhgef11,  M.musculus
Rho guanine nucleotide exchange factor (GEF) 11
    NP_001003912.1
1552 aa
   Arhgef11,  R.norvegicus
Rho guanine nucleotide exchange factor (GEF) 11
    NP_076472.1
1527 aa
   ARHGEF11,  G.gallus
Rho guanine nucleotide exchange factor (GEF) 11
    XP_423659.4
1166 aa
   arhgef11,  X.tropicalis
Rho guanine nucleotide exchange factor (GEF) 11
    XP_004917400.1
1607 aa
   arhgef11,  D.rerio
Rho guanine nucleotide exchange factor (GEF) 11
    NP_001027010.1
1417 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Expression of ARHGEF11 mRNA in schizophrenic thalamus.
Davidkova G, et al. Ann N Y Acad Sci 1003, 375-7 (2003).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
flgC (PRK12782)
  flagellar basal body rod protein FlgC; Reviewed.
RGS (cl02565)
  Regulator of G protein signaling (RGS) domain superfamily.
PDZ (cl00117)
  PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated. ...
RGS (cl02565)
  Regulator of G protein signaling (RGS) domain superfamily.
RhoGEF (cl02571)
  Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
PH-like (cl17171)
  Pleckstrin homology-like domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Arhgef11 includes H.sapiens ARHGEF11 and R.norvegicus Arhgef11.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (9 transcripts, 8 species)
Actinopterygii - bony fishes (5 transcripts, 3 species)
Amphibia - amphibians (3 transcripts, 2 species)
Aves - birds (1 transcript, 1 species)

 

 

 

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