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HomoloGene:13197. Gene conserved in Bilateria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   BBS4,  H.sapiens
Bardet-Biedl syndrome 4
    NP_149017.2
519 aa
   BBS4,  P.troglodytes
Bardet-Biedl syndrome 4
    XP_001175154.1
519 aa
   BBS4,  M.mulatta
Bardet-Biedl syndrome 4
    XP_001092858.2
507 aa
   BBS4,  C.lupus
Bardet-Biedl syndrome 4
    XP_005638770.1
613 aa
   BBS4,  B.taurus
Bardet-Biedl syndrome 4
    NP_001069424.1
519 aa
   Bbs4,  M.musculus
Bardet-Biedl syndrome 4 (human)
    NP_780534.1
520 aa
   Bbs4,  R.norvegicus
Bardet-Biedl syndrome 4
    NP_001100296.1
520 aa
   BBS4,  G.gallus
Bardet-Biedl syndrome 4
    NP_001264387.1
532 aa
   bbs4,  X.tropicalis
Bardet-Biedl syndrome 4
    NP_001016280.1
516 aa
   bbs4,  D.rerio
Bardet-Biedl syndrome 4
    NP_001070934.1
359 aa
   BBS4,  D.melanogaster
BBS4
    NP_610636.1
486 aa
   AgaP_AGAP004828,  A.gambiae
AgaP_AGAP004828
    XP_314365.4
434 aa
   CELE_F58A4.14,  C.elegans
CELE_F58A4.14
    NP_001255013.1
462 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Bardet-Biedl syndrome 4.



Publications
Articles associated with genes and sequences of this homology group.




Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
TPR_11 (pfam13414)
  TPR repeat.
TPR (cd00189)
  Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]-X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, ...
TPR (cl02429)
  Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]-X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, ...
TPR_11 (pfam13414)
  TPR repeat.
TPR_16 (pfam13432)
  Tetratricopeptide repeat.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Bbs4 includes H.sapiens BBS4 and R.norvegicus Bbs4.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (14 transcripts, 11 species)
Actinopterygii - bony fishes (7 transcripts, 6 species)
Ascidiacea - tunicates (2 transcripts, 2 species)
Aves - birds (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)
Amphibia - amphibians (1 transcript, 1 species)

Arthropoda
Insecta - insects (3 transcripts, 3 species)

Cnidaria
Hydrozoa - hydrozoans (2 transcripts, 2 species)
Anthozoa - anthozoans (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (2 transcripts, 2 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (1 transcript, 1 species)

Platyhelminthes
Trematoda - flatworms (1 transcript, 1 species)

Annelida
Hirudinida - segmented worms (1 transcript, 1 species)

Oomycetes
Peronosporales - oomycetes (1 transcript, 1 species)

Ciliophora
Oligohymenophorea - ciliates (1 transcript, 1 species)

 

 

 

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