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HomoloGene:20229. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   GRM2,  H.sapiens
glutamate receptor, metabotropic 2
    NP_000830.2
872 aa
   GRM2,  M.mulatta
glutamate receptor, metabotropic 2
    XP_001095565.1
872 aa
   GRM2,  C.lupus
glutamate receptor, metabotropic 2
    XP_541867.2
872 aa
   GRM2,  B.taurus
glutamate receptor, metabotropic 2
    NP_001192795.1
872 aa
   Grm2,  M.musculus
glutamate receptor, metabotropic 2
    NP_001153825.1
872 aa
   Grm2,  R.norvegicus
glutamate receptor, metabotropic 2
    NP_001099181.1
872 aa
   GRM2,  G.gallus
glutamate receptor, metabotropic 2
    XP_004944551.1
885 aa
   grm2,  X.tropicalis
glutamate receptor, metabotropic 2
    XP_004914127.1
864 aa
   grm2a,  D.rerio
glutamate receptor, metabotropic 2a
    XP_002662553.3
894 aa
   grm7,  D.rerio
glutamate receptor, metabotropic 7
    XP_005172969.1
874 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Interdomain movements in metabotropic glutamate receptor activation.
Huang S, et al. Proc Natl Acad Sci U S A 108, 15480-5 (2011).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
7tm_3 (pfam00003)
  7 transmembrane sweet-taste receptor of 3 GCPR.
NCD3G (pfam07562)
  Nine Cysteines Domain of family 3 GPCR.
7tm_3 (pfam00003)
  7 transmembrane sweet-taste receptor of 3 GCPR.
NCD3G (pfam07562)
  Nine Cysteines Domain of family 3 GPCR.
Periplasmic_Binding_Protein_Type_1 (cl10011)
  Type 1 periplasmic binding fold superfamily.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Grm2 includes H.sapiens GRM2 and R.norvegicus Grm2.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (12 transcripts, 10 species)
Actinopterygii - bony fishes (9 transcripts, 6 species)
Aves - birds (3 transcripts, 2 species)
Amphibia - amphibians (1 transcript, 1 species)

Arthropoda
Arachnida - arachnids (2 transcripts, 2 species)

Porifera
Demospongiae - sponges (2 transcripts, 1 species)

 

 

 

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