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HomoloGene:9487. Gene conserved in Boreoeutheria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   GHRL,  H.sapiens
ghrelin/obestatin prepropeptide
    NP_057446.1
117 aa
   GHRL,  P.troglodytes
ghrelin/obestatin prepropeptide
    XP_003339081.1
117 aa
   GHRL,  M.mulatta
ghrelin/obestatin prepropeptide
    NP_001028075.1
117 aa
   GHRL,  C.lupus
ghrelin/obestatin prepropeptide
    NP_001003052.1
117 aa
   GHRL,  B.taurus
ghrelin/obestatin prepropeptide
    NP_776492.1
116 aa
   Ghrl,  M.musculus
ghrelin
    NP_067463.2
117 aa
   Ghrl,  R.norvegicus
ghrelin/obestatin prepropeptide
    NP_067701.1
117 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Obesity, susceptibility to.



Publications
Articles associated with genes and sequences of this homology group.

Ghrelin triggers the synaptic incorporation of AMPA receptors in the hippocampus.
Ribeiro LF, et al. Proc Natl Acad Sci U S A 111, E149-58 (2014).
Association of plasma des-acyl ghrelin levels with CKD.
Gupta RK, et al. Clin J Am Soc Nephrol 8, 1098-105 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Motilin_assoc (pfam04643)
  Motilin/ghrelin-associated peptide.
Motilin_ghrelin (pfam04644)
  Motilin/ghrelin.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Ghrl includes H.sapiens GHRL and R.norvegicus Ghrl.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (7 transcripts, 7 species)

 

 

 

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