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HomoloGene:910. Gene conserved in Bilateria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   ARNTL,  H.sapiens
aryl hydrocarbon receptor nuclear translocator-like
    NP_001169.3
625 aa
   ARNTL,  P.troglodytes
aryl hydrocarbon receptor nuclear translocator-like
    XP_001171687.3
626 aa
   ARNTL,  M.mulatta
aryl hydrocarbon receptor nuclear translocator-like
    XP_002799675.1
626 aa
   ARNTL,  C.lupus
aryl hydrocarbon receptor nuclear translocator-like
    XP_005633740.1
632 aa
   ARNTL,  B.taurus
aryl hydrocarbon receptor nuclear translocator-like
    NP_001178099.1
626 aa
   Arntl,  M.musculus
aryl hydrocarbon receptor nuclear translocator-like
    NP_031515.1
626 aa
   Arntl,  R.norvegicus
aryl hydrocarbon receptor nuclear translocator-like
    NP_077338.2
626 aa
   ARNTL,  G.gallus
aryl hydrocarbon receptor nuclear translocator-like
    NP_001001463.1
633 aa
   arntl,  X.tropicalis
aryl hydrocarbon receptor nuclear translocator-like
    XP_002936788.2
502 aa
   cyc,  D.melanogaster
cycle
    NP_524168.2
413 aa
   AgaP_AGAP005655,  A.gambiae
AgaP_AGAP005655
    XP_556301.3
642 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Brain and muscle Arnt-like 1 is a key regulator of myogenesis.
Chatterjee S, et al. J Cell Sci 126, 2213-24 (2013).
O-GlcNAcylation of BMAL1 regulates circadian rhythms in NIH3T3 fibroblasts.
Ma YT, et al. Biochem Biophys Res Commun 431, 382-7 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
PAS (pfam00989)
  PAS fold.
PAS (cd00130)
  PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...
PAS_11 (pfam14598)
  PAS domain.
HLH (cl00081)
  Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Arntl includes H.sapiens ARNTL and R.norvegicus Arntl.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Actinopterygii - bony fishes (23 transcripts, 8 species)
Mammalia - mammals (15 transcripts, 12 species)
Aves - birds (3 transcripts, 3 species)
Amphibia - amphibians (3 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)

Arthropoda
Insecta - insects (11 transcripts, 10 species)

Echinodermata
Echinoidea - sea urchins (3 transcripts, 2 species)

Cnidaria
Hydrozoa - hydrozoans (1 transcript, 1 species)
Anthozoa - anthozoans (1 transcript, 1 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

Platyhelminthes
Trematoda - flatworms (1 transcript, 1 species)

 

 

 

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