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HomoloGene:9417. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   TMEFF2,  H.sapiens
transmembrane protein with EGF-like and two follistatin-like domains 2
    NP_057276.2
374 aa
   TMEFF2,  P.troglodytes
transmembrane protein with EGF-like and two follistatin-like domains 2
    XP_515997.2
374 aa
   TMEFF2,  M.mulatta
transmembrane protein with EGF-like and two follistatin-like domains 2
    XP_001084859.1
374 aa
   TMEFF2,  C.lupus
transmembrane protein with EGF-like and two follistatin-like domains 2
    XP_536010.2
374 aa
   TMEFF2,  B.taurus
transmembrane protein with EGF-like and two follistatin-like domains 2
    NP_001069569.1
374 aa
   Tmeff2,  M.musculus
transmembrane protein with EGF-like and two follistatin-like domains 2
    NP_062764.1
374 aa
   TMEFF2,  G.gallus
transmembrane protein with EGF-like and two follistatin-like domains 2
    XP_001231529.2
376 aa
   tmeff2a,  D.rerio
transmembrane protein with EGF-like and two follistatin-like domains 2a
    NP_001121837.1
379 aa
   tmeff2b,  D.rerio
transmembrane protein with EGF-like and two follistatin-like domains 2b
    XP_005165802.1
358 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

HPP1-mediated tumor suppression requires activation of STAT1 pathways.
Elahi A, et al. Int J Cancer 122, 1567-72 (2008).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
PHA02887 (PHA02887)
  EGF-like protein; Provisional.
KAZAL_FS (cl00097)
  Kazal type serine protease inhibitors and follistatin-like domains. Kazal inhibitors inhibit serine proteases, such as, trypsin, chyomotrypsin, avian ovomucoids, and elastases. The inhibitory domain has one reactive site peptide bond, which serves the ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Tmeff2 includes H.sapiens TMEFF2 and R.norvegicus Tmeff2.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (14 transcripts, 11 species)
Actinopterygii - bony fishes (7 transcripts, 6 species)
Aves - birds (2 transcripts, 2 species)
Amphibia - amphibians (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)

 

 

 

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