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HomoloGene:20870. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   DUSP3,  H.sapiens
dual specificity phosphatase 3
    NP_004081.1
185 aa
   DUSP3,  P.troglodytes
dual specificity phosphatase 3
    XP_003315464.1
185 aa
   DUSP3,  M.mulatta
dual specificity phosphatase 3
    XP_001113754.1
185 aa
   DUSP3,  C.lupus
dual specificity phosphatase 3
    XP_537624.3
240 aa
   DUSP3,  B.taurus
dual specificity phosphatase 3
    NP_001069842.1
203 aa
   Dusp3,  M.musculus
dual specificity phosphatase 3 (vaccinia virus phosphatase VH1-related)
    NP_082483.1
185 aa
   Dusp3,  R.norvegicus
dual specificity phosphatase 3
    NP_001166847.1
192 aa
   DUSP3,  G.gallus
dual specificity phosphatase 3
    XP_423280.4
137 aa
   LOC100498529,  X.tropicalis
dual specificity protein phosphatase 3-like
    XP_002937631.1
184 aa
   dusp3a,  D.rerio
dual specificity phosphatase 3a
    XP_001340818.2
200 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Crystal structure of the dual specificity protein phosphatase VHR.
Yuvaniyama J, et al. Science 272, 1328-31 (1996).
The catalytic role of Cys124 in the dual specificity phosphatase VHR.
Zhou G, et al. J Biol Chem 269, 28084-90 (1994).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
DSPc (cl00053)
  Dual specificity phosphatases (DSP); Ser/Thr and Tyr protein phosphatases. Structurally similar to tyrosine-specific phosphatases but with a shallower active site cleft and a distinctive active site signature motif, HCxxGxxR. Characterized as VHR- or ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Dusp3 includes H.sapiens DUSP3 and R.norvegicus Dusp3.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (11 transcripts, 11 species)
Actinopterygii - bony fishes (4 transcripts, 4 species)
Aves - birds (2 transcripts, 2 species)
Cephalochordata - lancelets (1 transcript, 1 species)
Amphibia - amphibians (1 transcript, 1 species)

Arthropoda
Arachnida - arachnids (1 transcript, 1 species)
Maxillopoda - crustaceans (1 transcript, 1 species)

Annelida
Polychaeta - segmented worms (2 transcripts, 1 species)

Echinodermata
Echinoidea - sea urchins (1 transcript, 1 species)

 

 

 

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