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HomoloGene:107244. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   VDAC1,  H.sapiens
voltage-dependent anion channel 1
    NP_003365.1
283 aa
   VDAC1,  P.troglodytes
voltage-dependent anion channel 1
    XP_001151901.2
283 aa
   VDAC1,  M.mulatta
voltage-dependent anion channel 1
    XP_001107652.1
283 aa
   VDAC1,  C.lupus
voltage-dependent anion channel 1
    XP_531907.1
283 aa
   VDAC1,  B.taurus
voltage-dependent anion channel 1
    NP_776910.2
283 aa
   Vdac1,  M.musculus
voltage-dependent anion channel 1
    NP_035824.1
283 aa
   Vdac1,  R.norvegicus
voltage-dependent anion channel 1
    NP_112643.1
283 aa
   VDAC1,  G.gallus
voltage-dependent anion channel 1
    NP_001029041.1
283 aa
   vdac1,  X.tropicalis
voltage-dependent anion channel 1
    NP_001016492.1
283 aa
   vdac1,  D.rerio
voltage-dependent anion channel 1
    NP_001001404.1
283 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

The role of lipids in VDAC oligomerization.
Betaneli V, et al. Biophys J 102, 523-31 (2012).
VDAC1 selectively transfers apoptotic Ca2+ signals to mitochondria.
De Stefani D, et al. Cell Death Differ 19, 267-73 (2012).
Brownian dynamics simulations of ion transport through the VDAC.
Lee KI, et al. Biophys J 100, 611-9 (2011).
Molecular dynamics studies of ion permeation in VDAC.
Rui H, et al. Biophys J 100, 602-10 (2011).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Porin3 (cl03224)
  Eukaryotic porin family that forms channels in the mitochondrial outer membrane.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Vdac1 includes H.sapiens VDAC1 and R.norvegicus Vdac1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (22 transcripts, 17 species)
Actinopterygii - bony fishes (17 transcripts, 10 species)
Aves - birds (2 transcripts, 2 species)
Cephalochordata - lancelets (2 transcripts, 1 species)
Amphibia - amphibians (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)
Ascidiacea - tunicates (1 transcript, 1 species)

Arthropoda
Insecta - insects (1 transcript, 1 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

Cnidaria
Anthozoa - anthozoans (1 transcript, 1 species)

 

 

 

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