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HomoloGene:37878. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   TIMM8A,  H.sapiens
translocase of inner mitochondrial membrane 8 homolog A (yeast)
    NP_004076.1
97 aa
   TIMM8A,  P.troglodytes
translocase of inner mitochondrial membrane 8 homolog A (yeast)
    XP_001139457.1
97 aa
   TIMM8A,  M.mulatta
translocase of inner mitochondrial membrane 8 homolog A (yeast)
    XP_001092722.1
97 aa
   TIMM8A,  C.lupus
translocase of inner mitochondrial membrane 8 homolog A (yeast)
    NP_001239296.1
97 aa
   TIMM8A,  B.taurus
translocase of inner mitochondrial membrane 8 homolog A (yeast)
    NP_001029652.1
97 aa
   Timm8a1,  M.musculus
translocase of inner mitochondrial membrane 8A1
    NP_038926.1
97 aa
   Timm8a1,  R.norvegicus
translocase of inner mitochondrial membrane 8 homolog A1 (yeast)
    NP_445822.1
97 aa
   TIMM8A,  G.gallus
translocase of inner mitochondrial membrane 8 homolog A (yeast)
    XP_420185.1
94 aa
   timm8a,  X.tropicalis
translocase of inner mitochondrial membrane 8 homolog A (yeast)
    XP_002940448.1
87 aa
   timm8a,  D.rerio
translocase of inner mitochondrial membrane 8 homolog A (yeast)
    NP_001003637.1
90 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Deafness, X-linked 1, progressive.
Mohr-Tranebjaerg syndrome.
Jensen syndrome.



Publications
Articles associated with genes and sequences of this homology group.

Deafness-Dystonia-Optic Neuronopathy Syndrome
Tranebjærg L, et al. (1993).
Dystonia with and without deafness is caused by TIMM8A mutation.
Swerdlow RH, et al. Adv Neurol 94, 147-54 (2004).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
zf-Tim10_DDP (pfam02953)
  Tim10/DDP family zinc finger.
zf-Tim10_DDP (pfam02953)
  Tim10/DDP family zinc finger.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Timm8a1 includes H.sapiens TIMM8A and R.norvegicus Timm8a1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (18 transcripts, 12 species)
Actinopterygii - bony fishes (7 transcripts, 6 species)
Aves - birds (2 transcripts, 2 species)
Amphibia - amphibians (2 transcripts, 2 species)
Cephalochordata - lancelets (1 transcript, 1 species)
Hyperoartia - vertebrates (1 transcript, 1 species)

Arthropoda
Branchiopoda - crustaceans (1 transcript, 1 species)

Cnidaria
Anthozoa - anthozoans (1 transcript, 1 species)

Porifera
Demospongiae - sponges (1 transcript, 1 species)

Annelida
Polychaeta - segmented worms (1 transcript, 1 species)

 

 

 

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