Display Settings:

Format

Send to:

Choose Destination
We are sorry, but NCBI web applications do not support your browser and may not function properly. More information
HomoloGene:1833. Gene conserved in Bilateria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   MSN,  H.sapiens
moesin
    NP_002435.1
577 aa
   MSN,  M.mulatta
moesin
    XP_001100546.2
577 aa
   MSN,  C.lupus
moesin
    XP_848336.1
577 aa
   MSN,  B.taurus
moesin
    NP_001039942.1
577 aa
   Msn,  M.musculus
moesin
    NP_034963.2
577 aa
   Msn,  R.norvegicus
moesin
    NP_110490.1
577 aa
   msn,  X.tropicalis
moesin
    XP_002936828.1
580 aa
   Moe,  D.melanogaster
Moesin
    NP_001259361.1
584 aa
   MOEH_ANOGA,  A.gambiae
MOEH_ANOGA
    XP_310518.5
578 aa
   erm-1,  C.elegans
erm-1
    NP_491559.1
563 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Moesin as a key cytoskeleton regulator in corneal fibrosis.
Zhu HY, et al. Ocul Surf 11, 119-32 (2013).
Knockdown of ERM family member moesin in host cells increases HIV type 1 replication.
Capalbo G, et al. AIDS Res Hum Retroviruses 27, 1317-22 (2011).
Moesin-induced signaling in response to lipopolysaccharide in macrophages.
Zawawi KH, et al. J Periodontal Res 45, 589-601 (2010).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
FERM_M (pfam00373)
  FERM central domain.
ERM (pfam00769)
  Ezrin/radixin/moesin family.
FERM_N (pfam09379)
  FERM N-terminal domain.
FERM_M (pfam00373)
  FERM central domain.
ERM (pfam00769)
  Ezrin/radixin/moesin family.
FERM_N (pfam09379)
  FERM N-terminal domain.
PH-like (cl17171)
  Pleckstrin homology-like domain.
SPFH_like (cl19107)
  core domain of the SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily.
ApoLp-III_like (cl19113)
  Apolipophorin-III and similar insect proteins.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Msn includes H.sapiens MSN and R.norvegicus Msn.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (10 transcripts, 10 species)
Actinopterygii - bony fishes (8 transcripts, 7 species)
Amphibia - amphibians (2 transcripts, 2 species)
Ascidiacea - tunicates (1 transcript, 1 species)
Aves - birds (1 transcript, 1 species)

Arthropoda
Insecta - insects (14 transcripts, 11 species)
Branchiopoda - crustaceans (2 transcripts, 1 species)
Arachnida - arachnids (1 transcript, 1 species)
Malacostraca - crustaceans (1 transcript, 1 species)
Maxillopoda - crustaceans (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (3 transcripts, 2 species)

Mollusca
Gastropoda - gastropods (2 transcripts, 1 species)

Platyhelminthes
Trematoda - flatworms (1 transcript, 1 species)
Turbellaria - flatworms (1 transcript, 1 species)

Cnidaria
Anthozoa - anthozoans (1 transcript, 1 species)

 

 

 

Write to the Help Desk