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HomoloGene:2981. Gene conserved in Bilateria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   ARRB1,  H.sapiens
arrestin, beta 1
    NP_004032.2
418 aa
   ARRB1,  P.troglodytes
arrestin, beta 1
    XP_508643.4
418 aa
   ARRB1,  M.mulatta
arrestin, beta 1
    XP_001083881.2
422 aa
   ARRB1,  C.lupus
arrestin, beta 1
    XP_005633548.1
421 aa
   ARRB1,  B.taurus
arrestin, beta 1
    NP_776668.1
418 aa
   Arrb1,  M.musculus
arrestin, beta 1
    NP_796205.1
418 aa
   Arrb1,  R.norvegicus
arrestin, beta 1
    NP_037042.1
418 aa
   LOC100486349,  X.tropicalis
beta-arrestin-1-like
    XP_004912283.1
461 aa
   arrb1,  D.rerio
arrestin, beta 1
    NP_001153294.1
418 aa
   krz,  D.melanogaster
kurtz
    NP_001247400.1
470 aa
   ARRK,  A.gambiae
ARRK
    XP_317960.1
431 aa
   arr-1,  C.elegans
arr-1
    NP_508183.1
435 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Functional map of arrestin-1 at single amino acid resolution.
Ostermaier MK, et al. Proc Natl Acad Sci U S A 111, 1825-30 (2014).
Crystal structure of pre-activated arrestin p44.
Kim YJ, et al. Nature 497, 142-6 (2013).
β-Arrestin-1 deficiency protects mice from experimental colitis.
Lee T, et al. Am J Pathol 182, 1114-23 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Arrestin_N (pfam00339)
  Arrestin (or S-antigen), N-terminal domain.
Arrestin_C (cl02844)
  Arrestin (or S-antigen), C-terminal domain.
Arrestin_N (cl19290)
  Arrestin (or S-antigen), N-terminal domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Arrb1 includes H.sapiens ARRB1 and R.norvegicus Arrb1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (12 transcripts, 10 species)
Actinopterygii - bony fishes (4 transcripts, 4 species)
Amphibia - amphibians (4 transcripts, 2 species)
Ascidiacea - tunicates (2 transcripts, 2 species)
Aves - birds (1 transcript, 1 species)
Hyperoartia - vertebrates (1 transcript, 1 species)

Arthropoda
Insecta - insects (9 transcripts, 7 species)
Arachnida - arachnids (2 transcripts, 1 species)
Branchiopoda - crustaceans (1 transcript, 1 species)

Platyhelminthes
Trematoda - flatworms (2 transcripts, 2 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

Cnidaria
Anthozoa - anthozoans (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (1 transcript, 1 species)

Annelida
Hirudinida - segmented worms (1 transcript, 1 species)

 

 

 

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