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HomoloGene:22826. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   NPHS2,  H.sapiens
nephrosis 2, idiopathic, steroid-resistant (podocin)
    NP_055440.1
383 aa
   NPHS2,  P.troglodytes
nephrosis 2, idiopathic, steroid-resistant (podocin)
    XP_003308663.2
383 aa
   NPHS2,  M.mulatta
nephrosis 2, idiopathic, steroid-resistant (podocin)
    XP_002802082.1
383 aa
   NPHS2,  C.lupus
nephrosis 2, idiopathic, steroid-resistant (podocin)
    XP_005623019.1
423 aa
   NPHS2,  B.taurus
nephrosis 2, idiopathic, steroid-resistant (podocin)
    NP_001193036.1
383 aa
   Nphs2,  M.musculus
nephrosis 2, podocin
    NP_569723.1
385 aa
   Nphs2,  R.norvegicus
nephrosis 2, idiopathic, steroid-resistant
    NP_570841.2
383 aa
   NPHS2,  G.gallus
nephrosis 2, idiopathic, steroid-resistant (podocin)
    XP_422265.3
384 aa
   nphs2,  X.tropicalis
nephrosis 2, idiopathic, steroid-resistant (podocin)
    XP_002937013.2
376 aa
   nphs2,  D.rerio
nephrosis 2, idiopathic, steroid-resistant (podocin)
    NP_001018155.1
390 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Nephrotic syndrome, idiopathic.
Nephrotic syndrome, steroid-resistant, autosomal recessive.



Publications
Articles associated with genes and sequences of this homology group.




Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Band_7_stomatin_like (cd03403)
  Band_7_stomatin_like: A subgroup of the band 7 domain of flotillin (reggie) like proteins similar to stomatin and podicin (two lipid raft-associated integral membrane proteins). Individual proteins of this band 7 domain family may cluster to form ...
SPFH_like (cl19107)
  core domain of the SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Nphs2 includes H.sapiens NPHS2 and R.norvegicus Nphs2.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (6 transcripts, 6 species)
Actinopterygii - bony fishes (1 transcript, 1 species)
Amphibia - amphibians (1 transcript, 1 species)

 

 

 

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