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HomoloGene:68078. Gene conserved in Bilateria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   ADRA1A,  H.sapiens
adrenoceptor alpha 1A
    NP_000671.2
466 aa
   ADRA1A,  P.troglodytes
adrenoceptor alpha 1A
    XP_003311731.1
429 aa
   ADRA1A,  M.mulatta
adrenoceptor alpha 1A
    NP_001108205.1
466 aa
   ADRA1A,  C.lupus
adrenoceptor alpha 1A
    NP_001182772.1
466 aa
   ADRA1A,  B.taurus
adrenergic, alpha-1A-, receptor
    NP_776923.1
466 aa
   Adra1a,  M.musculus
adrenergic receptor, alpha 1a
    NP_038489.2
466 aa
   Adra1a,  R.norvegicus
adrenoceptor alpha 1A
    NP_058887.2
466 aa
   ADRA1A,  G.gallus
adrenoceptor alpha 1A
    XP_425762.2
467 aa
   LOC100492776,  X.tropicalis
alpha-1A adrenergic receptor-like
    XP_002933012.2
489 aa
   LOC798498,  D.rerio
alpha-1A adrenergic receptor-like
    XP_001338938.2
485 aa
   Oamb,  D.melanogaster
Octopamine receptor in mushroom bodies
    NP_732542.1
645 aa
   GPROAR1,  A.gambiae
GPROAR1
    XP_311113.4
592 aa
   dop-4,  C.elegans
dop-4
    NP_508238.2
517 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Association of the ADRA1A gene and the severity of metabolic abnormalities in patients with schizophrenia.
Cheng C, et al. Prog Neuropsychopharmacol Biol Psychiatry 36, 205-10 (2012).
α-1 Adrenergic receptor signaling linked to memory dysfunction following brain trauma.
Tomycz ND & Friedlander RM. Neurosurgery 68, N16-8 (2011).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
7tm_1 (pfam00001)
  7 transmembrane receptor (rhodopsin family).
7tm_1 (pfam00001)
  7 transmembrane receptor (rhodopsin family).



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Adra1a includes H.sapiens ADRA1A and R.norvegicus Adra1a.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (11 transcripts, 10 species)
Actinopterygii - bony fishes (1 transcript, 1 species)
Aves - birds (1 transcript, 1 species)
Amphibia - amphibians (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (1 transcript, 1 species)

 

 

 

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