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HomoloGene:4363. Gene conserved in Boreoeutheria Download , Links
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins used in sequence comparisons and their conserved domain architectures.

   SNAI1,  H.sapiens
snail family zinc finger 1
264 aa
   SNAI1,  P.troglodytes
snail homolog 1 (Drosophila)
389 aa
   SNAI1,  M.mulatta
snail homolog 1 (Drosophila)
264 aa
   SNAI1,  C.lupus
snail family zinc finger 1
238 aa
   SNAI1,  B.taurus
snail homolog 1 (Drosophila)
264 aa
   Snai1,  M.musculus
snail homolog 1 (Drosophila)
264 aa
   Snai1,  R.norvegicus
snail family zinc finger 1
264 aa

Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments

Articles associated with genes and sequences of this homology group.

Snail cooperates with KrasG12D to promote pancreatic fibrosis.
Shields MA, et al. Mol Cancer Res 11, 1078-87 (2013).
Snail depletes the tumorigenic potential of glioblastoma.
Savary K, et al. Oncogene 32, 5409-20 (2013).
The role of Snail in prostate cancer.
Smith BN & Odero-Marah VA. Cell Adh Migr 6, 433-41 (2012).

Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
zf-H2C2_2 (pfam13465)
  Zinc-finger double domain.
zf-C2H2 (cl15478)
  Zinc finger, C2H2 type.
zf-C2H2 (pfam00096)
  Zinc finger, C2H2 type.
zf-H2C2_2 (cl19539)
  Zinc-finger double domain.

Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Snai1 includes H.sapiens SNAI1 and R.norvegicus Snai1.

Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Mammalia - mammals (9 transcripts, 8 species)
Actinopterygii - bony fishes (9 transcripts, 5 species)
Hyperoartia - vertebrates (1 transcript, 1 species)
Amphibia - amphibians (1 transcript, 1 species)

Turbellaria - flatworms (3 transcripts, 1 species)

Hydrozoa - hydrozoans (1 transcript, 1 species)
Anthozoa - anthozoans (1 transcript, 1 species)




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