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HomoloGene:398. Gene conserved in Boreoeutheria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   THPO,  H.sapiens
thrombopoietin
    NP_000451.1
353 aa
   THPO,  P.troglodytes
thrombopoietin
    XP_001136518.2
205 aa
   THPO,  C.lupus
thrombopoietin
    XP_005639837.1
352 aa
   THPO,  B.taurus
thrombopoietin
    NP_001159512.1
353 aa
   Thpo,  M.musculus
thrombopoietin
    NP_033405.1
356 aa
   LOC100910397,  R.norvegicus
thrombopoietin-like
    XP_006248642.1
478 aa
   Thpo,  R.norvegicus
thrombopoietin
    NP_112395.1
326 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Thrombocythemia, essential.



Publications
Articles associated with genes and sequences of this homology group.

Thrombopoietin and mean platelet volume in patients with ischemic stroke.
Balcik ÖS, et al. Clin Appl Thromb Hemost 19, 92-5 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
EPO_TPO (pfam00758)
  Erythropoietin/thrombopoietin.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Thpo includes H.sapiens THPO and R.norvegicus Thpo.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (6 transcripts, 6 species)

 

 

 

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