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HomoloGene:68992. Gene conserved in Bilateria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   GRIK1,  H.sapiens
glutamate receptor, ionotropic, kainate 1
    NP_000821.1
918 aa
   GRIK1,  P.troglodytes
glutamate receptor, ionotropic, kainate 1
    NP_001158174.1
918 aa
   GRIK1,  M.mulatta
glutamate receptor, ionotropic, kainate 1
    XP_002803199.1
920 aa
   GRIK1,  C.lupus
glutamate receptor, ionotropic, kainate 1
    XP_005638863.1
920 aa
   GRIK1,  B.taurus
glutamate receptor, ionotropic, kainate 1
    NP_001095984.1
905 aa
   Grik1,  M.musculus
glutamate receptor, ionotropic, kainate 1
    NP_666184.2
934 aa
   Grik1,  R.norvegicus
glutamate receptor, ionotropic, kainate 1
    NP_001104587.1
949 aa
   GRIK1,  G.gallus
glutamate receptor, ionotropic, kainate 1
    XP_004938435.1
894 aa
   grik1,  X.tropicalis
glutamate receptor, ionotropic, kainate 1
    XP_004912220.1
928 aa
   LOC561540,  D.rerio
glutamate receptor ionotropic, kainate 1-like
    XP_690040.5
906 aa
   CG11155,  D.melanogaster
CG11155
    NP_651941.2
910 aa
   CG9935,  D.melanogaster
CG9935
    NP_001036250.1
899 aa
   glr-5,  C.elegans
glr-5
    NP_505244.1
932 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Cortical GluK1 kainate receptors modulate scratching in adult mice.
Descalzi G, et al. J Neurochem 126, 636-50 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
PBPe (smart00079)
  Eukaryotic homologues of bacterial periplasmic substrate binding proteins.
Lig_chan (pfam00060)
  Ligand-gated ion channel.
PBPb (cd00134)
  Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic ...
Periplasmic_Binding_Protein_Type_1 (cl10011)
  Type 1 periplasmic binding fold superfamily.
Periplasmic_Binding_Protein_Type_1 (cl10011)
  Type 1 periplasmic binding fold superfamily.
TM_EphA1 (cl17164)
  Transmembrane domain of Ephrin Receptor A1 Protein Tyrosine Kinase.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Grik1 includes H.sapiens GRIK1 and R.norvegicus Grik1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (11 transcripts, 9 species)
Actinopterygii - bony fishes (6 transcripts, 4 species)
Aves - birds (3 transcripts, 2 species)
Amphibia - amphibians (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)

Arthropoda
Insecta - insects (14 transcripts, 8 species)
Maxillopoda - crustaceans (3 transcripts, 1 species)
Branchiopoda - crustaceans (1 transcript, 1 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

 

 

 

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