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HomoloGene:629. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

GABRA1,  H.sapiens
gamma-aminobutyric acid (GABA) A receptor, alpha 1
NP_000797.2
456 aa
GABRA1,  P.troglodytes
gamma-aminobutyric acid (GABA) A receptor, alpha 1
XP_001144644.2
477 aa
GABRA1,  M.mulatta
gamma-aminobutyric acid (GABA) A receptor, alpha 1
XP_002804660.1
477 aa
LOC489143,  C.lupus
gamma-aminobutyric acid receptor subunit alpha-1-like
XP_546261.2
456 aa
GABRA1,  B.taurus
gamma-aminobutyric acid (GABA) A receptor, alpha 1
NP_001178048.1
456 aa
Gabra1,  M.musculus
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1
NP_034380.1
455 aa
Gabra1,  R.norvegicus
gamma-aminobutyric acid (GABA) A receptor, alpha 1
NP_899155.1
455 aa
GABRA1,  G.gallus
gamma-aminobutyric acid (GABA) A receptor, alpha 1
NP_989649.1
455 aa
gabra1,  X.tropicalis
gamma-aminobutyric acid (GABA) A receptor, alpha 1
XP_002941682.2
453 aa
gabra1,  D.rerio
gamma-aminobutyric acid (GABA) A receptor, alpha 1
NP_001070794.1
459 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Epilepsy, juvenile myoclonic.



Publications
Articles associated with genes and sequences of this homology group.

[Relationship between gene polymorphism of GABAA receptors gene and childhood autism].
Lu GB, et al. Zhonghua Yu Fang Yi Xue Za Zhi 46, 460-4 (2012).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Neur_chan_memb (pfam02932)
  Neurotransmitter-gated ion-channel transmembrane region.
Neur_chan_LBD (pfam02931)
  Neurotransmitter-gated ion-channel ligand binding domain.
Neur_chan_memb (pfam02932)
  Neurotransmitter-gated ion-channel transmembrane region.
Neur_chan_LBD (pfam02931)
  Neurotransmitter-gated ion-channel ligand binding domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Gabra1 includes H.sapiens GABRA1 and R.norvegicus Gabra1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (14 transcripts, 11 species)
Actinopterygii - bony fishes (9 transcripts, 6 species)
Aves - birds (2 transcripts, 2 species)
Amphibia - amphibians (2 transcripts, 2 species)

Arthropoda
Insecta - insects (1 transcript, 1 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

 

 

 

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