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HomoloGene:55562. Gene conserved in Eukaryota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   CCNA2,  H.sapiens
cyclin A2
    NP_001228.1
432 aa
   CCNA2,  P.troglodytes
cyclin A2
    XP_517420.1
432 aa
   CCNA2,  M.mulatta
cyclin A2
    XP_001100860.1
432 aa
   CCNA2,  C.lupus
cyclin A2
    XP_540965.2
432 aa
   CCNA2,  B.taurus
cyclin A2
    NP_001068591.1
430 aa
   Ccna2,  M.musculus
cyclin A2
    NP_033958.2
422 aa
   Ccna2,  R.norvegicus
cyclin A2
    NP_446154.3
418 aa
   CCNA2,  G.gallus
cyclin A2
    NP_990575.1
395 aa
   ccna2,  X.tropicalis
cyclin A2
    NP_001006768.1
415 aa
   ccna2,  D.rerio
cyclin A2
    NP_694481.1
428 aa
   CycA,  D.melanogaster
Cyclin A
    NP_001246724.1
490 aa
   AgaP_AGAP012413,  A.gambiae
AgaP_AGAP012413
    XP_320142.3
350 aa
   CYCA2;3,  A.thaliana
CYCA2;3
    NP_173010.1
450 aa
   CYCA2;4,  A.thaliana
CYCA2;4
    NP_178153.1
461 aa
   Os12g0502300,  O.sativa
Os12g0502300
    NP_001066828.1
490 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

MicroRNA-124 targets CCNA2 and regulates cell cycle in STHdh(Q111)/Hdh(Q111) cells.
Das E, et al. Biochem Biophys Res Commun 437, 217-24 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Cyclin_C (pfam02984)
  Cyclin, C-terminal domain.
CYCLIN (cl00050)
  Cyclin box fold. Protein binding domain functioning in cell-cycle and transcription control. Present in cyclins, TFIIB and Retinoblastoma (RB).The cyclins consist of 8 classes of cell cycle regulators that regulate cyclin dependent kinases (CDKs). TFIIB ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Ccna2 includes H.sapiens CCNA2 and R.norvegicus Ccna2.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (13 transcripts, 11 species)
Actinopterygii - bony fishes (11 transcripts, 8 species)
Ascidiacea - tunicates (5 transcripts, 3 species)
Amphibia - amphibians (4 transcripts, 2 species)
Hyperoartia - vertebrates (3 transcripts, 1 species)
Aves - birds (1 transcript, 1 species)

Arthropoda
Insecta - insects (11 transcripts, 9 species)
Arachnida - arachnids (1 transcript, 1 species)

Mollusca
Gastropoda - gastropods (3 transcripts, 1 species)

Echinodermata
Echinoidea - sea urchins (3 transcripts, 2 species)

Cnidaria
Anthozoa - anthozoans (2 transcripts, 1 species)

Platyhelminthes
Trematoda - flatworms (1 transcript, 1 species)

Annelida
Polychaeta - segmented worms (1 transcript, 1 species)

Streptophyta
Eudicotyledons - eudicots (22 transcripts, 17 species)
Liliopsida - monocots (7 transcripts, 5 species)
Coniferopsida - conifers (2 transcripts, 1 species)

Ciliophora
Oligohymenophorea - ciliates (2 transcripts, 1 species)

 

 

 

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