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HomoloGene:99739. Gene conserved in Ascomycota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   MEC1,  S.cerevisiae
MEC1
    NP_009694.3
2368 aa
   KLLA0C15785g,  K.lactis
KLLA0C15785g
    XP_452905.1
2287 aa
   AGOS_ABR108C,  E.gossypii
AGOS_ABR108C
    NP_983055.2
2324 aa
   rad3,  S.pombe
rad3
    NP_595357.1
2386 aa
   MGG_02656,  M.oryzae
MGG_02656
    XP_003721126.1
2462 aa
   NCU11188,  N.crassa
NCU11188
    XP_001728458.1
2066 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Meiotic roles of Mec1, a budding yeast homolog of mammalian ATR/ATM.
Carballo JA & Cha RS. Chromosome Res 15, 539-50 (2007).
Clamping the Mec1/ATR checkpoint kinase into action.
Majka J & Burgers PM. Cell Cycle 6, 1157-60 (2007).
Hpz1 modulates the G1-S transition in fission yeast.
Bøe CA, et al. PLoS One 7, e44539 (2012).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
FATC (pfam02260)
  FATC domain.
FAT (pfam02259)
  FAT domain.
FAT (pfam02259)
  FAT domain.
FATC (pfam02260)
  FATC domain.
PI3Kc_like (cl00119)
  Phosphoinositide 3-kinase (PI3K)-like family, catalytic domain; The PI3K-like catalytic domain family is part of a larger superfamily that includes the catalytic domains of other kinases such as the typical serine/threonine/tyrosine protein kinases (PKs), ...
UME (cl06893)
  This domain is characteristic of UVSB PI-3 kinase, MEI-41 and ESR1.
HTH_42 (cl19833)
  Winged helix DNA-binding domain.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Streptophyta
Eudicotyledons - eudicots (3 transcripts, 3 species)
Liliopsida - monocots (1 transcript, 1 species)
Coniferopsida - conifers (1 transcript, 1 species)

Ascomycota
Sordariomycetes - ascomycetes (1 transcript, 1 species)
Eurotiomycetes - ascomycetes (1 transcript, 1 species)
Pezizomycetes - ascomycetes (1 transcript, 1 species)

Chordata
Mammalia - mammals (1 transcript, 1 species)

Bacillariophyta
Bacillariophyceae - diatoms (1 transcript, 1 species)

 

 

 

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