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HomoloGene:20579. Gene conserved in Opisthokonta Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   PFKP,  H.sapiens
phosphofructokinase, platelet
    NP_002618.1
784 aa
   PFKP,  C.lupus
phosphofructokinase, platelet
    XP_005617243.1
750 aa
   PFKP,  B.taurus
phosphofructokinase, platelet
    NP_001180149.1
791 aa
   Pfkp,  M.musculus
phosphofructokinase, platelet
    NP_062677.1
784 aa
   Pfkp,  R.norvegicus
phosphofructokinase, platelet
    NP_996729.1
788 aa
   pfkp,  X.tropicalis
phosphofructokinase, platelet
    NP_989217.1
802 aa
   pfkpb,  D.rerio
phosphofructokinase, platelet b
    XP_005163618.1
784 aa
   pfkpa,  D.rerio
phosphofructokinase, platelet a
    XP_005162583.1
789 aa
   PFK1,  S.cerevisiae
PFK1
    NP_011756.1
987 aa
   KLLA0A05544g,  K.lactis
KLLA0A05544g
    XP_451245.1
992 aa
   AGOS_AEL208W,  E.gossypii
AGOS_AEL208W
    NP_984653.1
987 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Phosphofructokinase C isozyme from ascites tumor cells: cloning, expression, and properties.
Sánchez-Martínez C, et al. Biochem Biophys Res Commun 271, 635-40 (2000).
Isolation and sequence of a cDNA encoding human platelet phosphofructokinase.
Simpson CJ & Fothergill-Gilmore LA. Biochem Biophys Res Commun 180, 197-203 (1991).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
6PF1K_euk (TIGR02478)
  6-phosphofructokinase, eukaryotic type.
PFK (cl00204)
  Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to PFK family that includes ATP- and pyrophosphate (PPi)- dependent phosphofructokinases. ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Pfkp includes H.sapiens PFKP and R.norvegicus Pfkp.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Actinopterygii - bony fishes (35 transcripts, 11 species)
Mammalia - mammals (16 transcripts, 15 species)
Aves - birds (3 transcripts, 3 species)
Amniota - vertebrates (1 transcript, 1 species)
Ascidiacea - tunicates (1 transcript, 1 species)
Hyperoartia - vertebrates (1 transcript, 1 species)

Arthropoda
Malacostraca - crustaceans (1 transcript, 1 species)

Apicomplexa
Coccidia - apicomplexans (1 transcript, 1 species)

 

 

 

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