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HomoloGene:285. Gene conserved in Bilateria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   SGCD,  H.sapiens
sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
    NP_000328.2
290 aa
   SGCD,  P.troglodytes
sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
    XP_001134904.2
290 aa
   LOC715190,  M.mulatta
delta-sarcoglycan-like
    XP_001113235.2
290 aa
   SGCD,  C.lupus
sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
    XP_005619314.1
289 aa
   SGCD,  B.taurus
sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
    NP_001178192.1
289 aa
   Sgcd,  M.musculus
sarcoglycan, delta (dystrophin-associated glycoprotein)
    NP_036021.1
289 aa
   Sgcd,  R.norvegicus
sarcoglycan, delta (dystrophin-associated glycoprotein)
    NP_001128298.1
289 aa
   SGCD,  G.gallus
sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
    XP_414572.1
292 aa
   sgcd,  X.tropicalis
sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
    XP_004912847.1
288 aa
   sgcd,  D.rerio
sarcoglycan, delta (dystrophin-associated glycoprotein)
    NP_001001816.1
289 aa
   Scgdelta,  D.melanogaster
Sarcoglycan delta
    NP_001162640.1
404 aa
   AgaP_AGAP000073,  A.gambiae
AgaP_AGAP000073
    XP_311082.5
278 aa
   sgn-1,  C.elegans
sgn-1
    NP_495867.1
334 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Muscular dystrophy, limb-girdle, type 2F.
Cardiomyopathy, dilated, 1L.



Publications
Articles associated with genes and sequences of this homology group.

Delta-sarcoglycan gene polymorphism frequency in Amerindian and Mestizo populations of Mexico.
Ordoñez-Razo RM, et al. Genet Test Mol Biomarkers 14, 237-40 (2010).
Intracellular Ca2+ transients in delta-sarcoglycan knockout mouse skeletal muscle.
Solares-Pérez A, et al. Biochim Biophys Acta 1800, 373-9 (2010).
Does delta-sarcoglycan-associated autosomal-dominant cardiomyopathy exist?
Bauer R, et al. Eur J Hum Genet 17, 1148-53 (2009).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Sarcoglycan_1 (pfam04790)
  Sarcoglycan complex subunit protein.
Sarcoglycan_1 (pfam04790)
  Sarcoglycan complex subunit protein.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Sgcd includes H.sapiens SGCD and R.norvegicus Sgcd.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (9 transcripts, 7 species)
Actinopterygii - bony fishes (7 transcripts, 6 species)
Cephalochordata - lancelets (2 transcripts, 1 species)
Aves - birds (1 transcript, 1 species)

Arthropoda
Insecta - insects (2 transcripts, 2 species)

Cnidaria
Hydrozoa - hydrozoans (1 transcript, 1 species)

 

 

 

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