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HomoloGene:1993. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   PLAG1,  H.sapiens
pleiomorphic adenoma gene 1
    NP_002646.2
500 aa
   PLAG1,  P.troglodytes
pleiomorphic adenoma gene 1
    XP_003311863.1
500 aa
   PLAG1,  M.mulatta
pleiomorphic adenoma gene 1
    XP_001085496.1
500 aa
   PLAG1,  C.lupus
pleiomorphic adenoma gene 1
    XP_005638057.1
499 aa
   PLAG1,  B.taurus
pleiomorphic adenoma gene 1
    XP_005215490.1
499 aa
   Plag1,  M.musculus
pleiomorphic adenoma gene 1
    NP_064353.2
499 aa
   Plag1,  R.norvegicus
pleiomorphic adenoma gene 1
    NP_001008317.1
499 aa
   PLAG1,  G.gallus
pleiomorphic adenoma gene 1
    NP_001026748.1
501 aa
   plag1,  X.tropicalis
pleiomorphic adenoma gene 1
    XP_004915248.1
499 aa
   plag1,  D.rerio
pleiomorphic adenoma gene 1
    NP_001034903.1
393 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Adenomas, salivary gland pleomorphic.
Pleomorphic salivary gland adenoma.



Publications
Articles associated with genes and sequences of this homology group.

Chromosomal rearrangements in PLAG1 of myoepithelial salivary gland tumours.
Friedrich RE, et al. Anticancer Res 32, 1977-81 (2012).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
zf-H2C2_2 (pfam13465)
  Zinc-finger double domain.
RING (cl17238)
  RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably ...
zf-H2C2_2 (cl19539)
  Zinc-finger double domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Plag1 includes H.sapiens PLAG1 and R.norvegicus Plag1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (5 transcripts, 5 species)
Actinopterygii - bony fishes (2 transcripts, 2 species)
Aves - birds (1 transcript, 1 species)

Arthropoda
Insecta - insects (1 transcript, 1 species)

 

 

 

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