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HomoloGene:4738. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   CLN5,  H.sapiens
ceroid-lipofuscinosis, neuronal 5
    NP_006484.1
407 aa
   CLN5,  P.troglodytes
ceroid-lipofuscinosis, neuronal 5
    XP_509687.3
407 aa
   CLN5,  M.mulatta
ceroid-lipofuscinosis, neuronal 5
    XP_001086029.2
481 aa
   CLN5,  C.lupus
ceroid-lipofuscinosis, neuronal 5
    NP_001011556.1
350 aa
   CLN5,  B.taurus
ceroid-lipofuscinosis, neuronal 5
    NP_001039764.1
358 aa
   Cln5,  M.musculus
ceroid-lipofuscinosis, neuronal 5
    NP_001028414.1
341 aa
   Cln5,  R.norvegicus
ceroid-lipofuscinosis, neuronal 5
    NP_001178618.1
341 aa
   RGD1564125,  R.norvegicus
similar to Cln5 protein
    XP_006232139.1
441 aa
   CLN5,  G.gallus
ceroid-lipofuscinosis, neuronal 5
    XP_004938692.1
339 aa
   cln5,  X.tropicalis
ceroid-lipofuscinosis, neuronal 5
    XP_002931974.2
333 aa
   LOC100335010,  D.rerio
ceroid-lipofuscinosis neuronal protein 5-like
    XP_002663389.1
329 aa
   cln5,  D.rerio
ceroid-lipofuscinosis, neuronal 5
    XP_697882.1
329 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Ceroid-lipofuscinosis, neuronal-5, variant late infantile.



Publications
Articles associated with genes and sequences of this homology group.

Identification of sites of mannose 6-phosphorylation on lysosomal proteins.
Sleat DE, et al. Mol Cell Proteomics 5, 686-701 (2006).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
CLN5 (pfam15014)
  Ceroid-lipofuscinosis neuronal protein 5.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Cln5 includes H.sapiens CLN5 and R.norvegicus RGD1564125.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (16 transcripts, 12 species)
Actinopterygii - bony fishes (6 transcripts, 6 species)
Aves - birds (3 transcripts, 2 species)
Amphibia - amphibians (2 transcripts, 2 species)

Platyhelminthes
Turbellaria - flatworms (1 transcript, 1 species)

 

 

 

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