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HomoloGene:10226. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   LGR4,  H.sapiens
leucine-rich repeat containing G protein-coupled receptor 4
    NP_060960.2
951 aa
   LGR4,  P.troglodytes
leucine-rich repeat containing G protein-coupled receptor 4
    XP_003313024.2
1090 aa
   LGR4,  M.mulatta
leucine-rich repeat containing G protein-coupled receptor 4
    XP_001090038.2
951 aa
   LGR4,  C.lupus
leucine-rich repeat containing G protein-coupled receptor 4
    XP_005633820.1
905 aa
   LGR4,  B.taurus
leucine-rich repeat containing G protein-coupled receptor 4
    NP_001192440.1
951 aa
   Lgr4,  M.musculus
leucine-rich repeat-containing G protein-coupled receptor 4
    NP_766259.2
951 aa
   Lgr4,  R.norvegicus
leucine-rich repeat-containing G protein-coupled receptor 4
    NP_775450.1
951 aa
   LGR4,  G.gallus
leucine-rich repeat containing G protein-coupled receptor 4
    XP_426162.3
952 aa
   lgr4,  X.tropicalis
leucine-rich repeat containing G protein-coupled receptor 4
    NP_001119970.1
955 aa
   lgr4,  D.rerio
leucine-rich repeat-containing G protein-coupled receptor 4
    XP_687184.4
971 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Schizophrenia, susceptibility to.



Publications
Articles associated with genes and sequences of this homology group.




Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
LRR_4 (pfam12799)
  Leucine Rich repeats (2 copies).
LRR_8 (pfam13855)
  Leucine rich repeat.
7tm_1 (pfam00001)
  7 transmembrane receptor (rhodopsin family).
PHA03087 (PHA03087)
  G protein-coupled chemokine receptor-like protein; Provisional.
LRRNT (cl02423)
  Leucine rich repeat N-terminal domain.
7tm_1 (pfam00001)
  7 transmembrane receptor (rhodopsin family).
LRR_8 (pfam13855)
  Leucine rich repeat.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Lgr4 includes H.sapiens LGR4 and R.norvegicus Lgr4.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (13 transcripts, 11 species)
Actinopterygii - bony fishes (2 transcripts, 2 species)
Amphibia - amphibians (2 transcripts, 2 species)
Aves - birds (1 transcript, 1 species)

 

 

 

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