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HomoloGene:22951. Gene conserved in Eukaryota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   MTMR2,  H.sapiens
myotubularin related protein 2
    NP_057240.3
643 aa
   MTMR2,  P.troglodytes
myotubularin related protein 2
    XP_508710.2
643 aa
   MTMR2,  M.mulatta
myotubularin related protein 2
    XP_001092784.1
643 aa
   MTMR2,  C.lupus
myotubularin related protein 2
    XP_848239.2
753 aa
   MTMR2,  B.taurus
myotubularin related protein 2
    NP_001095664.1
643 aa
   Mtmr2,  M.musculus
myotubularin related protein 2
    NP_076347.3
643 aa
   Mtmr2,  R.norvegicus
myotubularin related protein 2
    NP_001101593.1
643 aa
   MTMR2,  G.gallus
myotubularin related protein 2
    NP_001034363.1
571 aa
   mtmr2,  X.tropicalis
myotubularin related protein 2
    XP_002935623.2
570 aa
   mtmr2,  D.rerio
myotubularin related protein 2
    NP_571446.1
620 aa
   mtm,  D.melanogaster
myotubularin
    NP_523489.1
619 aa
   AgaP_AGAP009563,  A.gambiae
AgaP_AGAP009563
    XP_318571.3
583 aa
   AT3G10550,  A.thaliana
AT3G10550
    NP_187666.5
840 aa
   AT5G04540,  A.thaliana
AT5G04540
    NP_196074.2
833 aa
   Os08g0556700,  O.sativa
Os08g0556700
    NP_001062478.2
539 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Charcot-Marie-Tooth disease, type 4B1.



Publications
Articles associated with genes and sequences of this homology group.

An animal model for Charcot-Marie-Tooth disease type 4B1.
Bonneick S, et al. Hum Mol Genet 14, 3685-95 (2005).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Y_phosphatase_m (pfam13849)
  Myotubularin Y_phosphatase-like.
Myotub-related (pfam06602)
  Myotubularin-related.
Myotub-related (pfam06602)
  Myotubularin-like phosphatase domain.
PH-like (cl17171)
  Pleckstrin homology-like domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Mtmr2 includes H.sapiens MTMR2 and R.norvegicus Mtmr2.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (12 transcripts, 12 species)
Actinopterygii - bony fishes (10 transcripts, 7 species)
Aves - birds (2 transcripts, 2 species)
Amphibia - amphibians (2 transcripts, 1 species)
Ascidiacea - tunicates (1 transcript, 1 species)
Cephalochordata - lancelets (1 transcript, 1 species)

Arthropoda
Insecta - insects (13 transcripts, 9 species)
Arachnida - arachnids (3 transcripts, 1 species)
Maxillopoda - crustaceans (2 transcripts, 1 species)
Branchiopoda - crustaceans (1 transcript, 1 species)
Malacostraca - crustaceans (1 transcript, 1 species)

Mollusca
Gastropoda - gastropods (2 transcripts, 2 species)

Cnidaria
Hydrozoa - hydrozoans (1 transcript, 1 species)
Anthozoa - anthozoans (1 transcript, 1 species)

Platyhelminthes
Trematoda - flatworms (2 transcripts, 2 species)

Annelida
Hirudinida - segmented worms (1 transcript, 1 species)

Streptophyta
Eudicotyledons - eudicots (17 transcripts, 11 species)
Liliopsida - monocots (10 transcripts, 7 species)
Coniferopsida - conifers (1 transcript, 1 species)
Isoetopsida - club-mosses (1 transcript, 1 species)

Bacillariophyta
Bacillariophyceae - diatoms (1 transcript, 1 species)

Oomycetes
Peronosporales - oomycetes (1 transcript, 1 species)

Codonosigidae
Monosiga - choanoflagellates (1 transcript, 1 species)

 

 

 

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