Display Settings:

Format

Send to:

Choose Destination

Links from Gene

HomoloGene:4551. Gene conserved in Eukaryota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   PRKAA2,  H.sapiens
protein kinase, AMP-activated, alpha 2 catalytic subunit
    NP_006243.2
552 aa
   PRKAA2,  P.troglodytes
protein kinase, AMP-activated, alpha 2 catalytic subunit
    XP_001144587.1
552 aa
   PRKAA2,  M.mulatta
protein kinase, AMP-activated, alpha 2 catalytic subunit
    XP_002801614.1
491 aa
   PRKAA2,  C.lupus
protein kinase, AMP-activated, alpha 2 catalytic subunit
    XP_005620393.1
533 aa
   PRKAA2,  B.taurus
protein kinase, AMP-activated, alpha 2 catalytic subunit
    NP_001192534.1
552 aa
   Prkaa2,  M.musculus
protein kinase, AMP-activated, alpha 2 catalytic subunit
    NP_835279.2
552 aa
   Prkaa2,  R.norvegicus
protein kinase, AMP-activated, alpha 2 catalytic subunit
    NP_076481.1
552 aa
   PRKAA2,  G.gallus
protein kinase, AMP-activated, alpha 2 catalytic subunit
    NP_001034694.1
552 aa
   prkaa2,  X.tropicalis
protein kinase, AMP-activated, alpha 2 catalytic subunit
    NP_001135554.1
551 aa
   prkaa2,  D.rerio
protein kinase, AMP-activated, alpha 2 catalytic subunit
    XP_700831.4
553 aa
   SNF1A,  D.melanogaster
SNF1A/AMP-activated protein kinase
    NP_477313.1
582 aa
   AgaP_AGAP002686,  A.gambiae
AgaP_AGAP002686
    XP_312237.4
565 aa
   aak-2,  C.elegans
aak-2
    NP_510710.2
626 aa
   SNF1,  S.cerevisiae
SNF1
    NP_010765.3
633 aa
   KLLA0A03806g,  K.lactis
KLLA0A03806g
    XP_451166.1
602 aa
   AGOS_AEL230W,  E.gossypii
AGOS_AEL230W
    NP_984631.1
608 aa
   ssp2,  S.pombe
ssp2
    NP_588376.1
576 aa
   MGG_00803,  M.oryzae
MGG_00803
    XP_003718181.1
803 aa
   NCU04566,  N.crassa
NCU04566
    XP_958665.2
706 aa
   Os03g0289100,  O.sativa
Os03g0289100
    NP_001049790.1
508 aa
   Os08g0484600,  O.sativa
Os08g0484600
    NP_001062083.1
509 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

AMPK and insulin action--responses to ageing and high fat diet.
Frøsig C, et al. PLoS One 8, e62338 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
UBA_2 (pfam08587)
  Ubiquitin associated domain (UBA).
S_TKc (smart00220)
  Serine/Threonine protein kinases, catalytic domain.
UBA_2 (pfam08587)
  Ubiquitin associated domain (UBA).
UBA (cl00153)
  Ubiquitin Associated domain. The UBA domain is a commonly occurring sequence motif in some members of the ubiquitination pathway, UV excision repair proteins, and certain protein kinases. Although its specific role is so far unknown, it has been suggested that UBA domains are involved in conferring protein target specificity. The domain, a compact three helix bundle, has a conserved GFP-loop and the proline is thought to be critical for binding. The UBA domain is distinct from the conserved three helical domain seen in the N-terminus of EF-TS and eukaryotic NAC proteins.
AMPKA_C_like (cl17070)
  C-terminal regulatory domain of 5'-AMP-activated protein kinase (AMPK) alpha subunit and similar domains.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Prkaa2 includes H.sapiens PRKAA2 and R.norvegicus Prkaa2.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (10 transcripts, 10 species)
Aves - birds (3 transcripts, 3 species)
Ascidiacea - tunicates (1 transcript, 1 species)
Actinopterygii - bony fishes (1 transcript, 1 species)
Amphibia - amphibians (1 transcript, 1 species)

Arthropoda
Insecta - insects (10 transcripts, 10 species)
Arachnida - arachnids (2 transcripts, 2 species)
Branchiopoda - crustaceans (1 transcript, 1 species)
Malacostraca - crustaceans (1 transcript, 1 species)
Maxillopoda - crustaceans (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (2 transcripts, 2 species)

Platyhelminthes
Trematoda - flatworms (2 transcripts, 2 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

Cnidaria
Anthozoa - anthozoans (1 transcript, 1 species)

Porifera
Demospongiae - sponges (1 transcript, 1 species)

Annelida
Hirudinida - segmented worms (1 transcript, 1 species)

Streptophyta
Liliopsida - monocots (20 transcripts, 9 species)
Eudicotyledons - eudicots (3 transcripts, 2 species)
Isoetopsida - club-mosses (1 transcript, 1 species)

Ascomycota
Sordariomycetes - ascomycetes (3 transcripts, 3 species)
Eurotiomycetes - ascomycetes (1 transcript, 1 species)
Pezizomycetes - ascomycetes (1 transcript, 1 species)

 

 

 

Write to the Help Desk