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HomoloGene:18739. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   DFNB31,  H.sapiens
deafness, autosomal recessive 31
    NP_056219.3
907 aa
   DFNB31,  P.troglodytes
deafness, autosomal recessive 31
    XP_001145880.3
987 aa
   DFNB31,  M.mulatta
deafness, autosomal recessive 31
    XP_001096493.2
907 aa
   DFNB31,  C.lupus
deafness, autosomal recessive 31
    XP_005627013.1
938 aa
   DFNB31,  B.taurus
deafness, autosomal recessive 31
    XP_005210632.1
918 aa
   Whrn,  M.musculus
whirlin
    NP_001008793.1
906 aa
   Dfnb31,  R.norvegicus
deafness, autosomal recessive 31
    NP_851602.1
920 aa
   DFNB31,  G.gallus
deafness, autosomal recessive 31
    XP_427028.4
865 aa
   dfnb31,  X.tropicalis
deafness, autosomal recessive 31
    XP_004916786.1
899 aa
   LOC100334777,  D.rerio
whirlin-like
    XP_002665968.3
939 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Deafness, autosomal recessive 31.



Publications
Articles associated with genes and sequences of this homology group.




Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
HN_L-whirlin_R2_like (cd07357)
  Second harmonin_N_like domain (repeat 2) of the long isoform of whirlin, and related domains.
HN_L-whirlin_R1_like (cd07356)
  First harmonin_N_like domain (repeat 1) of the long isoform of whirlin, and related domains.
harmonin_N_like (cl11968)
  N-terminal protein-binding module of harmonin and similar domains.
PDZ (cl00117)
  PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated. ...
harmonin_N_like (cl11968)
  N-terminal protein-binding module of harmonin and similar domains, also known as HHD (harmonin homology domain).



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Whrn includes H.sapiens DFNB31 and R.norvegicus Cip98.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (9 transcripts, 7 species)
Actinopterygii - bony fishes (6 transcripts, 5 species)
Amphibia - amphibians (3 transcripts, 2 species)
Aves - birds (1 transcript, 1 species)

Cnidaria
Anthozoa - anthozoans (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (1 transcript, 1 species)

 

 

 

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