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HomoloGene:2393. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   T,  H.sapiens
T, brachyury homolog (mouse)
    NP_003172.1
435 aa
   T,  P.troglodytes
T, brachyury homolog (mouse)
    XP_527563.3
435 aa
   T,  M.mulatta
T, brachyury homolog (mouse)
    XP_001101514.1
435 aa
   T,  C.lupus
T, brachyury homolog (mouse)
    NP_001003092.1
435 aa
   T,  B.taurus
T, brachyury homolog (mouse)
    NP_001179914.1
435 aa
   T,  M.musculus
brachyury
    NP_033335.1
436 aa
   T,  R.norvegicus
brachyury
    NP_001099679.1
436 aa
   T,  G.gallus
T, brachyury homolog (mouse)
    NP_990271.1
433 aa
   t,  X.tropicalis
T, brachyury homolog
    NP_001008139.1
434 aa
   LOC100004296,  D.rerio
novel protein similar to murine T brachyury (T)
    XP_001343633.3
424 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Neural tube defects, susceptibility to.



Publications
Articles associated with genes and sequences of this homology group.

Genome-wide association identifies the T gene as a novel asthma pharmacogenetic locus.
Tantisira KG, et al. Am J Respir Crit Care Med 185, 1286-91 (2012).
Extra-axial soft tissue chordoma of wrist.
Suzuki H, et al. Pathol Res Pract 207, 327-31 (2011).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
TBOX (cl00145)
  T-box DNA binding domain of the T-box family of transcriptional regulators. The T-box family is an ancient group that appears to play a critical role in development in all animal species. These genes were uncovered on the basis of similarity to the DNA ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus T includes H.sapiens T and R.norvegicus T.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (9 transcripts, 7 species)
Amphibia - amphibians (6 transcripts, 2 species)
Actinopterygii - bony fishes (3 transcripts, 3 species)
Ascidiacea - tunicates (2 transcripts, 2 species)
Cephalochordata - lancelets (2 transcripts, 1 species)
Aves - birds (1 transcript, 1 species)

Cnidaria
Hydrozoa - hydrozoans (3 transcripts, 2 species)
Anthozoa - anthozoans (1 transcript, 1 species)

Arthropoda
Insecta - insects (3 transcripts, 3 species)

Porifera
Demospongiae - sponges (2 transcripts, 1 species)

Echinodermata
Echinoidea - sea urchins (2 transcripts, 2 species)

 

 

 

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