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HomoloGene:20223. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   GAD2,  H.sapiens
glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
    NP_000809.1
585 aa
   GAD2,  P.troglodytes
glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
    XP_001157825.1
585 aa
   GAD2,  M.mulatta
glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
    XP_002805636.1
585 aa
   GAD2,  C.lupus
glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
    NP_001070907.1
585 aa
   GAD2,  B.taurus
glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
    NP_001192652.1
585 aa
   Gad2,  M.musculus
glutamic acid decarboxylase 2
    NP_032104.2
585 aa
   Gad2,  R.norvegicus
glutamate decarboxylase 2
    NP_036695.1
585 aa
   GAD2,  G.gallus
glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
    XP_418596.3
396 aa
   gad2,  X.tropicalis
glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
    XP_002933179.1
588 aa
   gad2,  D.rerio
glutamate decarboxylase 2
    NP_001017708.2
583 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Disruption of centrifugal inhibition to olfactory bulb granule cells impairs olfactory discrimination.
Nunez-Parra A, et al. Proc Natl Acad Sci U S A 110, 14777-82 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
AAT_I (cl18945)
  Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Gad2 includes H.sapiens GAD2 and R.norvegicus Gad2.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (9 transcripts, 9 species)
Actinopterygii - bony fishes (7 transcripts, 5 species)
Amphibia - amphibians (4 transcripts, 2 species)
Aves - birds (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)

Ascomycota
Pezizomycetes - ascomycetes (1 transcript, 1 species)

 

 

 

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