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HomoloGene:56504. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   MYO15A,  H.sapiens
myosin XVA
    NP_057323.3
3530 aa
   MYO15A,  P.troglodytes
myosin XVA
    XP_003315632.1
3439 aa
   MYO15A,  M.mulatta
myosin XVA
    XP_002800352.1
3390 aa
   MYO15A,  C.lupus
myosin XVA
    XP_536660.3
3519 aa
   MYO15A,  B.taurus
myosin XVA
    XP_002707808.1
3511 aa
   Myo15,  M.musculus
myosin XV
    NP_034992.2
3511 aa
   Myo15a,  R.norvegicus
myosin XVA
    XP_006246612.1
3420 aa
   MYO15A,  G.gallus
myosin XVA
    XP_004945420.1
3026 aa
   myo15a,  X.tropicalis
myosin XVA
    XP_002935902.2
3004 aa
   myo15aa,  D.rerio
myosin XVAa
    XP_001924051.2
2393 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Deafness, autosomal recessive 3.



Publications
Articles associated with genes and sequences of this homology group.

Spontaneous mutant ICR kuru2 might be another shaker-2 deaf mouse.
Watanabe M, et al. In Vivo 26, 787-91 (2012).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Herpes_UL56 (pfam04534)
  Herpesvirus UL56 protein.
SnAPC_2_like (pfam11035)
  Small nuclear RNA activating complex subunit 2-like.
Dscam_C (pfam12355)
  Down syndrome cell adhesion molecule C terminal.
B41 (smart00295)
  Band 4.1 homologues.
FERM_M (pfam00373)
  FERM central domain.
Motor_domain (cl00286)
  Myosin and Kinesin motor domain. These ATPases belong to the P-loop NTPase family and provide the driving force in myosin and kinesin mediated processes.
PH-like (cl17171)
  Pleckstrin homology-like domain.
SH3 (cl17036)
  Src Homology 3 domain superfamily.
FERM_M (pfam00373)
  FERM central domain.
MFMR (pfam07777)
  G-box binding protein MFMR.
Motor_domain (cl00286)
  Myosin and Kinesin motor domain. These ATPases belong to the P-loop NTPase family and provide the driving force in myosin and kinesin mediated processes.
MyTH4 (cl02480)
  MyTH4 domain.
SH3 (cl17036)
  Src Homology 3 domain superfamily.
PH-like (cl17171)
  Pleckstrin homology-like domain.
ApoLp-III_like (cl19113)
  Apolipophorin-III and similar insect proteins.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Myo15 includes H.sapiens MYO15A and R.norvegicus Myo15.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (6 transcripts, 6 species)
Actinopterygii - bony fishes (3 transcripts, 3 species)

 

 

 

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