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HomoloGene:56542. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   TENM1,  H.sapiens
teneurin transmembrane protein 1
    NP_001156750.1
2732 aa
   ODZ1,  P.troglodytes
odz, odd Oz/ten-m homolog 1 (Drosophila)
    XP_003317714.1
2710 aa
   ODZ1,  M.mulatta
odz, odd Oz/ten-m homolog 1 (Drosophila)
    XP_002806432.1
2732 aa
   TENM1,  C.lupus
teneurin transmembrane protein 1
    XP_865135.1
2732 aa
   ODZ1,  B.taurus
odz, odd Oz/ten-m homolog 1 (Drosophila)
    NP_001243484.1
2659 aa
   Tenm1,  M.musculus
teneurin transmembrane protein 1
    NP_035985.2
2731 aa
   Tenm1,  R.norvegicus
teneurin transmembrane protein 1
    XP_006257573.1
2673 aa
   ODZ1,  G.gallus
odz, odd Oz/ten-m homolog 1 (Drosophila)
    NP_990193.1
2705 aa
   tenm1,  X.tropicalis
teneurin transmembrane protein 1
    XP_002931868.2
2681 aa
   LOC563094,  D.rerio
novel protein similar to vertebrate odz, odd Oz/ten-m (Drosophila) family
    XP_691552.5
2721 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Teneurin proteins possess a carboxy terminal sequence with neuromodulatory activity.
Wang L, et al. Brain Res Mol Brain Res 133, 253-65 (2005).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Ten_N (pfam06484)
  Teneurin Intracellular Region.
EGF_2 (pfam07974)
  EGF-like domain.
RhsA (COG3209)
  Rhs family protein [Cell envelope biogenesis, outer membrane].
Rhs_assc_core (TIGR03696)
  RHS repeat-associated core domain.
EGF_CA (cl09941)
  Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
RHS_repeat (cl11982)
  RHS Repeat.
Ten_N (pfam06484)
  Teneurin Intracellular Region.
EGF_2 (pfam07974)
  EGF-like domain.
Tox-GHH (pfam15636)
  GHH signature containing HNH/Endo VII superfamily nuclease toxin.
EGF_CA (cl09941)
  Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
RHS_repeat (cl11982)
  RHS proteins contain extended repeat regions. These repeats often appear to be involved in ligand binding. Note that this model may not find all the repeats in a protein and that it covers two RHS repeats.
Peptidase_M14NE-CP-C_like (cl17499)
  Peptidase associated domain: C-terminal domain of M14 N/E carboxypeptidase; putative folding, regulation, or interaction domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Tenm1 includes H.sapiens TENM1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (14 transcripts, 8 species)
Actinopterygii - bony fishes (5 transcripts, 5 species)
Amniota - vertebrates (1 transcript, 1 species)
Aves - birds (1 transcript, 1 species)
Amphibia - amphibians (1 transcript, 1 species)

 

 

 

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